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Showing papers by "Leslie Hyman published in 2023"


Journal ArticleDOI
TL;DR: In this paper , the authors investigated causes of childhood blindness in the United States using the IRIS Registry (Intelligent Research in Sight) and found that more than one-half of blind patients had a treatable cause of blindness.

2 citations


Journal ArticleDOI
TL;DR: In this paper , the authors evaluated demographic risk factors and visual acuity (VA) outcomes of open-globe injuries requiring surgical repair in the IRIS® Registry (Intelligent Research in Sight).

Journal ArticleDOI
TL;DR: In this article , a data-cleaning strategy was developed to infer patients' corrected distance visual acuity in their better-seeing eye from 2018 IRIS Registry records, and the IRIS registry Chicago dataset contains 168,920,049 visual acity records among 23,001,531 unique patients and 49,968,974 unique patient visit dates in 2018.
Abstract: To describe visual acuity data representation in the American Academy of Ophthalmology IRIS® Registry (Intelligent Research In Sight) and present a data-cleaning strategy Reliability and Validity Study Patients with visual acuity records from 2018 in the IRIS Registry Visual acuity measurements and metadata were identified and characterized from 2018 IRIS Registry records. Metadata, including laterality, assessment method (distance, near, unspecified), correction (corrected, uncorrected, unspecified), and flags for refraction or pinhole assessment were compared between Rome (frozen 4/20/2020) and Chicago (frozen 12/24/2021) versions. We developed a data-cleaning strategy to infer patients’ corrected distance visual acuity in their better-seeing eye. Visual acuity data characteristics in the IRIS Registry The IRIS Registry Chicago dataset contains 168,920,049 visual acuity records among 23,001,531 unique patients and 49,968,974 unique patient visit dates in 2018. Visual acuity records were associated with refraction in 5.3% of cases, and with pinhole in 11.0%. Mean (SD) of all measurements was 0.26 (0.41) logMAR, with a range of -0.3 to 4.0 A plurality of visual acuity records were labeled corrected (CVA; 39.1%), followed by unspecified (37.6%) and uncorrected (UCVA; 23.4%). CVA measurements were paradoxically worse than same-day UCVA 15% of the time. In aggregate, mean and median values were similar for CVA and unspecified visual acuity. Most visual acuity measurements were at distance (59.8%, versus 32.1% unspecified and 8.2% near). Rome contained more duplicate visual acuity records than Chicago (10.8% versus 1.4%). Near visual acuity was classified with Jaeger notation and (in Chicago only) also assigned logMAR values by Verana Health. LogMAR values for hand motion and light perception visual acuity were lower in Chicago than in Rome. Impact of data entry errors or outliers on analyses may be reduced by filtering and averaging visual acuity per eye over time. The IRIS Registry includes similar visual acuity metadata in Rome and Chicago. Although fewer duplicate records were found in Chicago, both versions include duplicate and atypical measurements (i.e., CVA worse than UCVA on the same day). Analyses may benefit from using algorithms to filter outliers and average visual acuity measurements over time.


Journal ArticleDOI
TL;DR: In this paper , the authors report the incidence of and evaluate demographic, ocular comorbidities, and intraoperative factors for rhegmatogenous retinal detachment and retinal tear after cataract surgery in the American Academy of Ophthalmology IRIS® Registry (Intelligent Research in Sight).
Abstract: To report the incidence of and evaluate demographic, ocular comorbidities, and intraoperative factors for rhegmatogenous retinal detachment (RRD) and retinal tear (RT) after cataract surgery in the American Academy of Ophthalmology IRIS® Registry (Intelligent Research in Sight).Retrospective cohort study.Patients aged ≥ 40 years who underwent cataract surgery between 2014 and 2017.Multivariable logistic regression was used to evaluate demographic, comorbidity, and intraoperative factors associated with RRD and RT after cataract surgery.Incidence and risk factors for RRD or RT within 1 year of cataract surgery.Of the 3 177 195 eyes of 1 983 712 patients included, 6690 (0.21%) developed RRD and 5489 (0.17%) developed RT without RRD within 1 year after cataract surgery. Multivariable logistic regression odds ratios (ORs) showed increased risk of RRD and RT, respectively, among men (OR 3.15; 95% confidence interval [CI], 2.99-3.32; P < 0.001 and 1.79; 95% CI, 1.70-1.89; P < 0.001), and younger ages compared with patients aged > 70, peaking at age 40 to 50 for RRD (8.61; 95% CI, 7.74-9.58; P < 0.001) and age 50 to 60 for RT (2.74; 95% CI, 2.52-2.98; P < 0.001). Increased odds of RRD were observed for procedure eyes with lattice degeneration (LD) (10.53; 95% CI, 9.82-11.28; P < 0.001), hypermature cataract (1.61; 95% CI, 1.06-2.45; P = 0.03), complex cataract surgery (1.52; 95% CI, 1.4-1.66; P < 0.001), posterior vitreous detachment (PVD) (1.24; 95% CI, 1.15-1.34; P < 0.001), and high myopia (1.2; 95% CI, 1.14-1.27; P < 0.001). Lattice degeneration conferred the highest odds of RT (43.86; 95% CI, 41.39-46.49; P < 0.001).In the IRIS Registry, RRD occurs in approximately 1 in 500 cataract surgeries in patients aged > 40 years within 1 year of surgery. The presence of LD conferred the highest odds for RRD and RT after surgery. Additional risk factors for RRD included male gender, younger age, hypermature cataract, PVD, and high myopia. These data may be useful during the informed consent process for cataract surgery and help identify patients at a higher risk of retinal complications.The author(s) have no proprietary or commercial interest in any materials discussed in this article.

Journal ArticleDOI
TL;DR: The JAMA Ophthalmology journal published by the American Medical Association (AMA) as mentioned in this paper is the most widely cited journal in the field of ophthalmology, with a circulation of more than 6 million copies.
Abstract: Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Ophthalmology HomeNew OnlineCurrent IssueFor Authors Podcast Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Ophthalmology journal

Journal ArticleDOI
TL;DR: In this article , the authors evaluated associations of patient characteristics with United States eyecare utilization and likelihood of blindness and proposed a multivariable logistic regression model evaluated blindness and visually impaired (VI) associations.

Journal ArticleDOI
TL;DR: In this paper , the authors evaluated the prevalence of thyroid eye disease (TED) and associated factors in the American Academy of Ophthalmology IRISⓇ Registry (Intelligent Research in Sight).