Leticia Reyes

TL;DR: A novel phenomenon present in P. gingivalis-induced FGR is shown, with relevance to human disease since dysregulation of placental Htra1 and placental oxidative stress are features of preeclamptic placentas and preeclampsia with FGR.

TL;DR: It is found that the rat oral microbiome profiles were more similar to that of the human oral cavity compared to previous reports targeting one or two 16S variable regions, and there appears to be a relatively stable core microbiome in the oral cavity.

TL;DR: It is shown that a PG_RS02100 deletion mutant’s ability to grow under anaerobic conditions was no different than wildtype, but it was better able to survive hydrogen peroxide exposure when cultured under heme limiting growth conditions, and was more aerotolerant when plated on enriched whole blood agar and exposed to atmospheric oxygen.

TL;DR: In this paper, the authors investigated lower nicotine doses and found that 1 mg/kg/d nicotine dose decreased risk of intrauterine infection, with increased maternal and fetal inflammatory responses (MIR and FIR).

TL;DR: Elevated body weight and cardiovascular reactivity in the PNI offspring was associated with an increase in the ratio of hypothalamic corticotrophin-releasing hormone receptors Type 1: Type 2 gene expression in both sexes compared to controls.