L
Letizia Clementi
Researcher at University of L'Aquila
Publications - 10
Citations - 127
Letizia Clementi is an academic researcher from University of L'Aquila. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 4, co-authored 7 publications receiving 51 citations.
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Journal ArticleDOI
Src Family Kinases as Therapeutic Targets in Advanced Solid Tumors: What We Have Learned so Far.
Stefano Martellucci,Letizia Clementi,Samantha Sabetta,Vincenzo Mattei,Lorenzo Botta,Adriano Angelucci +5 more
TL;DR: Basic molecular mechanisms involving SFKs in cancer spreading and metastasization are summarized; and preclinical and clinical data highlighting the main challenges for their future application as therapeutic targets in solid cancer progression are discussed.
Journal ArticleDOI
In Vitro Conditioning Determines the Capacity of Dental Pulp Stem Cells to Function as Pericyte-Like Cells.
Simona Delle Monache,Stefano Martellucci,Stefano Martellucci,Letizia Clementi,Fanny Pulcini,Francesca Santilli,Cecilia Mei,Luca Piccoli,Adriano Angelucci,Vincenzo Mattei +9 more
TL;DR: Dental pulp has been revealed as an accessible and a rich source of mesenchymal stem cells (MSCs) and its biological potential is currently under intense investigation.
Journal ArticleDOI
Chemically stable inhibitors of 14-3-3 protein-protein interactions derived from BV02.
Leire Iralde-Lorente,Ylenia Cau,Letizia Clementi,Lorenzo Franci,G. Tassone,Daniela Valensin,Mattia Mori,Adriano Angelucci,Mario Chiariello,Maurizio Botta +9 more
TL;DR: The privileged 4-aminoantipyrine scaffold is exploited in the design and synthesis of some derivatives endowed with antiproliferative activity against K-562 cells, and capable of binding to recombinant 14-3-3σ as evidenced by NMR spectroscopy.
Book ChapterDOI
Leptin in Tumor Microenvironment
TL;DR: The main mechanisms that regulate peripheral leptin availability and how leptin can shape tumor microenvironment are described.
Journal ArticleDOI
Identification of Phosphate-Containing Compounds as New Inhibitors of 14-3-3/c-Abl Protein-Protein Interaction.
Leire Iralde-Lorente,G. Tassone,Letizia Clementi,Lorenzo Franci,Claire C. Munier,Ylenia Cau,Mattia Mori,Mario Chiariello,Adriano Angelucci,Perry Matthew,Cecilia Pozzi,Stefano Mangani,Maurizio Botta +12 more
TL;DR: The data suggest that 14-3-3σ targeting compounds represent promising hits for further development of drugs against c-Abl-dependent cancers.