L
Li Gao
Researcher at Harbin Veterinary Research Institute
Publications - 101
Citations - 1418
Li Gao is an academic researcher from Harbin Veterinary Research Institute. The author has contributed to research in topics: Infectious bursal disease & Virus. The author has an hindex of 16, co-authored 100 publications receiving 889 citations.
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Journal ArticleDOI
Novel variant strains of infectious bursal disease virus isolated in China.
Linjin Fan,Tiantian Wu,Altaf Hussain,Yulong Gao,Xianying Zeng,Yulong Wang,Li Gao,Kai Li,Yongqiang Wang,Changjun Liu,Hongyu Cui,Qing Pan,Yanping Zhang,Yufeng Liu,Hongjiang He,Xiaomei Wang,Xiaole Qi +16 more
TL;DR: This study identified the pandemic nature of the novel variant IBDVs for the first time but also discovered the distinct molecular epidemiological characteristics of these viruses, which will contribute more to the control of the disease.
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Naturally occurring mutations at residues 253 and 284 in VP2 contribute to the cell tropism and virulence of very virulent infectious bursal disease virus
TL;DR: Dual evidence from natural and rescued strains identified that the cell tropism of vvIBDV to CEF cells was determined by the combined VP2 mutations Q253H and A284T, but not by single mutation, which were mainly responsible for the virulence of IBDV.
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Avian oncogenic herpesvirus antagonizes the cGAS-STING DNA-sensing pathway to mediate immune evasion.
Kai Li,Yongzhen Liu,Zengkun Xu,Yu Zhang,Dan Luo,Yulong Gao,Yingjuan Qian,Chenyi Bao,Changjun Liu,Yanping Zhang,Xiaole Qi,Hongyu Cui,Yongqiang Wang,Li Gao,Xiaomei Wang +14 more
TL;DR: It is revealed that Marek’s disease virus evades the cGAS-STING DNA sensing pathway, which underpins the efficient replication and oncogenesis.
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Novel variants of infectious bursal disease virus can severely damage the bursa of fabricius of immunized chickens
Linjin Fan,Tiantian Wu,Yulong Wang,Altaf Hussain,Nan Jiang,Li Gao,Kai Li,Yulong Gao,Changjun Liu,Hongyu Cui,Qing Pan,Yanping Zhang,Xiaomei Wang,Xiaole Qi +13 more
TL;DR: This study determined the primary reason for the atypical IBD epidemic, and reminded us of the urgency for developing new vaccines against novel variant IBDV.
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Characterization of a hypervirulent fowl adenovirus 4 with the novel genotype newly prevalent in China and establishment of reproduction infection model of hydropericardium syndrome in chickens.
Qing Pan,Linlin Liu,Yanni Gao,Changjun Liu,Xiaole Qi,Yao Zhang,Yongqiang Wang,Kai Li,Li Gao,Xiurong Wang,Hongyu Cui +10 more
TL;DR: The study revealed that HLJFAd15 was identified with the novel genotype strains recently emerging in China by complete genome sequencing, and the strain was capable of causing HPS by the pathogenicity analysis.