Background—Age-related dementia, most commonly caused by Alzheimer disease or cerebrovascular factors (vascular dementia), is a major public health threat. Chronic arterial hypertension is a well-e...

Impact of Hypertension on Cognitive Function: A Scientific Statement From the American Heart Association

自身免疫性垂体炎是一种罕见的内分泌疾病,多发生于妊娠或产后.其发病机制不明,临床表现多变,主要包括垂体压迫、腺垂体功能减退症、尿崩症和高催乳素血症等相关症状.治疗目的主要是减小垂体肿块的大小和(或)替代有缺陷的内分泌功能.多数患者需要长期使用激素替代治疗。

Autoimmune hypophysitis

Why is obesity such a problem in the 21st century? The intersection of palatable food, cues and reward pathways, stress, and cognition

The increasing prevalence of multifocal cerebral microhemorrhages (CMHs, also known as “cerebral microbleeds”) is a significant, newly recognized problem in the aging population of the Western worl...

https://www.physiology.org/doi/pdf/10.1152/ajpheart.00780.2016

Cerebral microhemorrhages: mechanisms, consequences, and prevention

:The clinical and pathological features of 63 steroid cell tumors, not otherwise specified, were reviewed. The patients ranged in age from 2'A to 80 years. The most common initial manifestation was virilization (41%); four patients had estrogenic manifestations, and four had hypercortisolemi

Ovarian Steroid Cell Tumors (Not Otherwise Specified): A Clinicopathological Analysis of 63 Cases

Objective To compare the accordance between the diagnostic criteria of metabolic syndrome (MS) by International Diabetes Federation (IDF) and that by Chinese Medical Association (CMA) Diabetes Branch Methods An epidemiological survey on diabetes mellitus (DM) was conducted among 2344 residents in Shijingshan community, Beijing, aged >or= 40 1870 of these 2344 people, 901 males and 969 females, without DM underwent physical examination, laboratory tests, questionnaire survey and oral glucose tolerance test so as to screen the MS patients by both diagnostic criteria The accordance of these 2 criteria was analyzed statistically by using the STATA70 software Results The accordance rate of these 2 MS diagnostic criteria was 7995% If the criterion for fasting blood glucose in the China criteria was adjusted to 56 mmol/L, the accordance increased to 8139% 1091 persons were diagnosed as with central obesity according to the IDF criteria, 626 of which could be diagnosed as central obesity according to the China criteria with an accordance rate of 5738% Out of these 1091 persons 578 (923%) had the BMI >or= 25 kg/m(2) Out of the 779 persons that failed to be diagnosed as with central obesity 113 persons were diagnosed as with central obesity according to the China criteria Fifty of these 113 persons had the BMI >or= 25 kg/m(2) 111 persons diagnosed as with MS did not have BMI abnormality According to the IDF criteria, the morbidity of myocardial infarction (MI) and/or cerebral stroke in those with MS was 1987%, significantly higher than in those without MS (1486%, P = 0004), and according to the China criteria, the morbidity of myocardial infarction (MI) and/or cerebral stroke in those with MS was 1952%, significantly higher than in those without MS (1521%, P = 0013) as well There was no significant difference in the morbidity of MI and cerebral stroke between the IDF criteria and China criteria (P = 0092) According to the IDF criteria the morbidity of microalbuminuria in the MS patients was 859%, significantly higher than that in the persons without MS (428%, P = 0000) According to the China criteria the morbidity of microalbuminuria in the MS patients was 855%, significantly higher than that in the persons without MS (449%, P = 0000) There was no significant difference in the morbidity of microalbuminuria between these 2 criteria (P = 0976) There were no significant difference in the morbidity of microalbuminuria in the persons with central obesity and those with the BMI >or= 25 kg/m(2) between these 2 criteria (P = 077) Conclusion The MS diagnostic criteria of IDF and that of CMA Diabetes Branch are in good accordance

Comparison of the diagnostic criteria of metabolic syndrome by International Diabetes Federation and that by Chinese Medical Association Diabetes Branch

Objective
Pituitary stalk interruption syndrome (PSIS) is characterized by the absence of pituitary stalk, pituitary hypoplasia, and ectopic posterior pituitary. Due to the rarity of PSIS, clinical data are limited, especially in Chinese people. Herein, we analyzed the clinical characteristics of patients diagnosed with PSIS from our center over 10 years.

/pdf/pituitary-stalk-interruption-syndrome-in-chinese-people-gsqrnu7shj.pdf

Pituitary stalk interruption syndrome in Chinese people: clinical characteristic analysis of 55 cases

Cerebral microbleeds (CMBs) and white matter hyperintensities (WMH) are the most common manifestations of small vessel disease, and often co-occur in patients with cerebral vascular disease. Hypertension is widely accepted as a risk factor for both CMBs and WMH. However, the effect of hypertension on the association between CMBs and WMH remains unclear. We hypothesized that the relationship between CMBs and WMH is determined by hypertension. One hundred forty-eight patients with acute cerebrovascular disease who were admitted to PLA general hospital in Beijing, China from February 2010 to May 2011 were recruited in this study. CMBs on T2*-weighted angiography (SWAN) were assessed using the Brain Observer Microbleed Rating Scale criteria. The severity of the WMH was separately assessed as either peri-ventricular hyperintensities (PVH) or deep white matter hyperintensities (DWMH). The association among CMBs and the severity of WMH, and hypertension were determined. CMBs were found in 65 (43.9%) patients. The frequency of CMBs was related to the severity of DWMH and PVH. CMBs were more frequently observed in patients with hypertension compared to patients without hypertension (51.3% vs. 20.0%, p = 0.001). Hypertension was an independent risk factor for CMBs (odds ratio 5.239, p = 0.001) and DWMH (odds ratio 2.373, p = 0.040). Furthermore, the relationship between the presence of CMBs and the severity of DWMH was only found in patients with hypertension (r = 0.298, p<0.01). However, CMBs were associated with PVH independently of hypertension. This study demonstrated that hypertension determined the association between CMBs and DWMH.

/pdf/cerebral-microbleeds-are-associated-with-deep-white-matter-3c3ovfaghd.pdf

Cerebral Microbleeds Are Associated with Deep White Matter Hyperintensities, but Only in Hypertensive Patients

Characterization of papillary thyroid microcarcinomas using sonographic features in malignant papillary thyroid cancer: a retrospective analysis.

Objectives: To evaluate the relationship of cognitive function with glucose tolerance status and obesity in Chinese middle-aged or aged adults. Methods: A sample of 1722 subjects aged 40 years or order was investigated from four communities in Shijingshan District, Beijing, China. People with any emotional disorder, substance abuse, known diabetes or stroke were excluded. Global cognitive function was measured by the Mini-Mental State Examination (MMSE). Results: People with normal glucose tolerance showed higher mean MMSE scores compared to those with pre-diabetes or diabetes (p > 0.05 in males, p < 0.05 in females). People with ideal BMI (18.5–23.9) showed higher mean MMSE scores compared to those with BMI < 18.5 or BMI ≥ 24, but there was no statistical significance (p < 0.05) The significantly lower MMSE scores was shown in the groups with waist circumferences ≥ 85 cm in males, or ≥ 80 cm in females (p < 0.05). The multivariate linear regression analysis showed significant association of MMSE with wai...

Li-juan Yang

Papers

Comparison of the diagnostic criteria of metabolic syndrome by International Diabetes Federation and that by Chinese Medical Association Diabetes Branch

Pituitary stalk interruption syndrome in Chinese people: clinical characteristic analysis of 55 cases

Cerebral Microbleeds Are Associated with Deep White Matter Hyperintensities, but Only in Hypertensive Patients

Characterization of papillary thyroid microcarcinomas using sonographic features in malignant papillary thyroid cancer: a retrospective analysis.

Cognitive function with glucose tolerance status and obesity in Chinese middle-aged and aged adults.