L
Li Wan
Researcher at Nanjing Medical University
Publications - 7
Citations - 914
Li Wan is an academic researcher from Nanjing Medical University. The author has contributed to research in topics: Gene knockdown & Carcinogenesis. The author has an hindex of 7, co-authored 7 publications receiving 779 citations.
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Journal ArticleDOI
Long noncoding RNA PVT1 indicates a poor prognosis of gastric cancer and promotes cell proliferation through epigenetically regulating p15 and p16
Rong Kong,Erbao Zhang,Dandan Yin,Lianghui You,Tongpeng Xu,Wen-ming Chen,Rui Xia,Li Wan,Ming Sun,Zhaoxia Wang,Wei De,Zhihong Zhang +11 more
TL;DR: This is the first report showed that the role and the mechanism of PVT1 in the progression of gastric cancer is shown and suggests that lncRNA PVT 1 may serve as a candidate prognostic biomarker and target for new therapies in human Gastric cancer.
Journal ArticleDOI
Long Noncoding RNA PVT1 Promotes Non-Small Cell Lung Cancer Cell Proliferation through Epigenetically Regulating LATS2 Expression.
Li Wan,Ming Sun,Guo-Jian Liu,Chenchen Wei,Erbao Zhang,Rong Kong,Tongpeng Xu,Ming-de Huang,Zhaoxia Wang +8 more
TL;DR: Functional analysis revealed that knockdown of PVT1 inhibited NSCLC cell proliferation and induced apoptosis both in vitro and in vivo, and indicated that PVT 1/EZH2/LATS2 interactions might serve as new target for lung adenocarcinoma diagnosis and therapy.
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The Long Noncoding RNA MEG3 Contributes to Cisplatin Resistance of Human Lung Adenocarcinoma.
TL;DR: It is demonstrated that MEG3 is significantly downregulated in LAD and partially regulates the cisplatin resistance of LAD cells through the control of p53 and Bcl-xl expression.
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Long intergenic non-coding RNA 00152 promotes lung adenocarcinoma proliferation via interacting with EZH2 and repressing IL24 expression
Qinnan Chen,Xin Chen,Zhenyao Chen,Fengqi Nie,Chenchen Wei,Hongwei Ma,Li Wan,Shuai Yan,Sheng-nan Ren,Zhaoxia Wang +9 more
TL;DR: In this article, the authors used RNA transcriptome sequencing technology to identify the downstream suppressor IL24 (interleukin 24) which was further examined by qRT-PCR, western bolt and rescue experiments.
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CircRNAs in anticancer drug resistance: recent advances and future potential
TL;DR: This review is the first to summarize the latest research on circRNAs in anticancer drug resistance based on drug classification and to discuss their potential clinical applications.