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Ming Sun

Researcher at University of Texas MD Anderson Cancer Center

Publications -  68
Citations -  10144

Ming Sun is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Cancer & Cell growth. The author has an hindex of 47, co-authored 64 publications receiving 8856 citations. Previous affiliations of Ming Sun include Nanjing Medical University.

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Long non-coding RNAs: A new frontier in the study of human diseases

TL;DR: The rapidly advancing field of lncRNAs is reviewed and the relationship between the dysregulation of l NCRNAs and human diseases is described, highlighting the specific roles of lNCRNAs in human diseases.
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Lnc RNA HOTAIR functions as a competing endogenous RNA to regulate HER2 expression by sponging miR-331-3p in gastric cancer

TL;DR: The ceRNA regulatory network involving HOTAIR and the positive interaction between HotaIR and HER2 may contribute to a better understanding of gastric cancer pathogenesis and facilitate the development of lncRNA-directed diagnostics and therapeutics against this disease.
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LncRNA HOXA11-AS Promotes Proliferation and Invasion of Gastric Cancer by Scaffolding the Chromatin Modification Factors PRC2, LSD1, and DNMT1.

TL;DR: Findings support a model in which the EZH2/HOXA11-AS/LSD1 complex and HOXA 11- AS/miR-1297/EZh2 cross-talk serve as critical effectors in gastric cancer tumorigenesis and progression, suggesting new therapeutic directions in gastrics cancer.
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Long non-coding RNA MEG3 inhibits NSCLC cells proliferation and induces apoptosis by affecting p53 expression

TL;DR: MEG3 expression was decreased in non-small cell lung cancer (NSCLC) tumor tissues compared with normal tissues, and associated with advanced pathologic stage, and tumor size, which indicates that MEG3 may represent a new marker of poor prognosis and is a potential therapeutic target for NSCLC intervention.