L
Liam Berry
Researcher at University of Manitoba
Publications - 7
Citations - 136
Liam Berry is an academic researcher from University of Manitoba. The author has contributed to research in topics: Antibiotics & Efflux. The author has an hindex of 4, co-authored 6 publications receiving 51 citations.
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Journal ArticleDOI
Omadacycline: A Novel Oral and Intravenous Aminomethylcycline Antibiotic Agent
George G. Zhanel,Jenine Esquivel,Sheryl A. Zelenitsky,Courtney K. Lawrence,Heather J. Adam,Alyssa R Golden,Rachel Hink,Liam Berry,Frank Schweizer,Michael A. Zhanel,Denice C. Bay,Philippe Lagacé-Wiens,Andrew Walkty,Joseph P. Lynch,James A. Karlowsky +14 more
TL;DR: Omadacycline possesses broad-spectrum antibacterial activity against Gram-positive and Gram-negative aerobic, anaerobic, and atypical bacteria, and remains active against bacterial isolates possessing common tetracyCline resistance mechanisms such as efflux pumps and ribosomal protection proteins.
Journal ArticleDOI
Dilipid Ultrashort Tetrabasic Peptidomimetics Potentiate Novobiocin and Rifampicin Against Multidrug-Resistant Gram-Negative Bacteria
TL;DR: Results indicate that polybasic peptidomimetic-based adjuvants repurpose novobiocin and rifampicin as potent agents against priority MDR Gram-negative pathogens.
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Lefamulin: A Novel Oral and Intravenous Pleuromutilin for the Treatment of Community-Acquired Bacterial Pneumonia
George G. Zhanel,Christina Deng,Sheryl A. Zelenitsky,Courtney K. Lawrence,Heather J. Adam,Alyssa R Golden,Liam Berry,Frank Schweizer,Michael A. Zhanel,Neal Irfan,Denice C. Bay,Philippe Lagacé-Wiens,Andrew Walkty,Lionel A. Mandell,Joseph P. Lynch,James A. Karlowsky +15 more
TL;DR: Lefamulin represents a safe and effective option for treating CABP in cases of antimicrobial resistance to first-line therapies, clinical failure, or intolerance/adverse effects to currently used agents.
Journal ArticleDOI
Development of dilipid polymyxins: Investigation on the effect of hydrophobicity through its fatty acyl component.
TL;DR: An understanding to the polymyxin structure is provided that may be used to usher the development of enhanced polymyXin analogs, suggesting that the lipid component of poly myxin plays an important role in resisting active efflux.
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Polybasic peptide-levofloxacin conjugates potentiate fluoroquinolones and other classes of antibiotics against multidrug-resistant Gram-negative bacteria.
TL;DR: The synthesis of polybasic peptide-levofloxacin conjugates based on antibiotic hybrids consisting of tobramycin appended to different fluoroquinolones that possess potential as stand-alone antimicrobials as well as adjuvants are reported.