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Lifeng Zhang

Researcher at National University of Singapore

Publications -  11
Citations -  261

Lifeng Zhang is an academic researcher from National University of Singapore. The author has contributed to research in topics: Cyclodextrin & Staudinger reaction. The author has an hindex of 6, co-authored 11 publications receiving 253 citations.

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A facile immobilization approach for perfunctionalised cyclodextrin onto silica via the Staudinger reaction

TL;DR: The Staudinger reaction was applied for the first time in the immobilization of mono-(6-azido-6-deoxy)-perfunctionalised cyclodextrins onto the surface of aminised silica gel under mild conditions as discussed by the authors.
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Synthesis and chromatographic properties of a novel chiral stationary phase derived from heptakis(6-azido-6-deoxy-2,3-di-O-phenylcarbamoylated)-β-cyclodextrin immobilized onto amino-functionalized silica gel via multiple urea linkages

TL;DR: A novel chiral stationary phase (PPHCDN7) was prepared by immobilization of heptakis(6-azido-6-deoxy-2,3-di-O-phenylcarbamoylated)-beta-cyclodextrin onto the surface of amino-functionalized silica gel via multiple urea linkages derived from an extended application of the Staudinger reaction.
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A facile route into 6A-mono-ω-alkenylcarbamido-6A-deoxy-perfunctionalised cyclodextrin: key intermediate for further reactive functionalisations

TL;DR: The Staudinger reaction was applied to the facile synthetic generation of a series of mono-6-alkylcarbamido- 6-deoxy-perfunctionalised cyclodextrins and mono-8-ω-alkenyl carbamido -6-de oxygen-per functionalised cyclodesxtrin compounds to afford reactive siloxane intermediates which can be immobilised onto silica gel for application as an efficient chiral stationary phase for enantioseparation
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Facile preparative HPLC enantioseparation of racemic drugs using chiral stationary phases based on mono-6A-azido-6A-deoxy-perphenylcarbamoylated β-cyclodextrin immobilized on silica gel

TL;DR: In this paper, the Staudinger reaction was used for enantioseparation of racemic mixtures using atropine, bendroflumethiazide and four β-adrenergic blocking agents under reversed phase conditions.
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Preparation and study of two polysiloxanes with pendant hand-basket type calixarene stationary phases for capillary gas chromatography

TL;DR: In this paper, two novel pendant hand-basket type calixarene gas chromatography stationary phases were prepared by hydrosilylation of ω-undecenyloxymethyl dimethyl calix[4]-15C5 and ωundecnyloxyclic oxymethyl-15C6 with dichloromethane followed by condensation reaction with silanol-terminated polydimethylsiloxane.