L
Lili Liu
Researcher at Fourth Military Medical University
Publications - 45
Citations - 1389
Lili Liu is an academic researcher from Fourth Military Medical University. The author has contributed to research in topics: Cancer & Cell cycle. The author has an hindex of 19, co-authored 39 publications receiving 1223 citations.
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Journal ArticleDOI
Hypoxia‐inducible factor‐1α contributes to hypoxia‐induced chemoresistance in gastric cancer
Lili Liu,Xiaoxuan Ning,Li Sun,Hongbo Zhang,Yongquan Shi,Changcun Guo,Shuang Han,Jie Liu,Shiren Sun,Zheyi Han,Kaichun Wu,Daiming Fan +11 more
TL;DR: Hypoxia‐inducible factor‐1 (HIF‐1), the major transcriptional factor significantly activated by hypoxia, was overexpressed in gastric vincristine‐resistant cells SGC7901/vinc Bristine (VCR) under normoxic conditions, which suggested that it was associated with drug resistance in Gastric cancer cells.
Journal ArticleDOI
Hypoxia-inducible factor-1α induces Twist expression in tubular epithelial cells subjected to hypoxia, leading to epithelial-to-mesenchymal transition
Shiren Sun,Xiaoxuan Ning,Yanqi Zhang,Yuanyuan Lu,Yongzhan Nie,Shuang Han,Lili Liu,Rui Du,Lin Xia,He Lijie,Daiming Fan +10 more
TL;DR: It is suggested that HIF-1alpha induces Twist expression in hypoxic tubular cells and that this plays a role in EMT during renal fibrogenesis.
Journal ArticleDOI
KLF8 involves in TGF-beta-induced EMT and promotes invasion and migration in gastric cancer cells.
Hui Zhang,Lili Liu,Yafang Wang,Guohong Zhao,Rougang Xie,Changhao Liu,Xiao Xiao,Kaichun Wu,Yongzhan Nie,Hongbo Zhang,Daiming Fan +10 more
TL;DR: KLF8, a transcription factor, is involved in TGF-β1-induced EMT in Gastric cancer cells and may be a novel therapeutic target for the treatment of gastric cancer.
Journal ArticleDOI
Hypoxia-inducible lncRNA-AK058003 promotes gastric cancer metastasis by targeting γ-synuclein.
Yafang Wang,Xiangqiang Liu,Hongbo Zhang,Li Sun,Yongan Zhou,Haifeng Jin,Hongwei Zhang,Hui Zhang,Jiaming Liu,Hao Guo,Yongzhan Nie,Kaichun Wu,Daiming Fan,Helong Zhang,Lili Liu +14 more
TL;DR: The results advance the understanding of the role of lncRNA-AK058003 as a regulator of hypoxia signaling, and this newly identifiedhypoxia/lnc RNA-AK58003/SNCG pathway may help in the development of new therapeutics.
Journal ArticleDOI
Three dysregulated microRNAs in serum as novel biomarkers for gastric cancer screening
Hui Wang,Lei Wang,Zheng Wu,Rong Sun,Haifeng Jin,Jifeng Ma,Lili Liu,Rui Ling,Jun Yi,Ling Wang,Jie-fang Bian,Jianghao Chen,Nanlin Li,Shifang Yuan,Jun Yun +14 more
TL;DR: Significantly elevated expression of the three miRNAs was also observed in advanced GC patients, which suggested their availability in cancer staging, and confirmed the diagnostic value of serum miR-223, mi-16, and mi-100 in GC.