Lillian Kang

TL;DR: Partial heart transplantation can be performed using donor hearts with poor ventricular function and slow progression to donation after cardiac death and should ameliorate donor heart utilization and avoid both primary orthotopic heart transplants in children with unrepairable heart valve dysfunction and progression of these children to end-stage heart failure.

TL;DR: In this article, an experimental epidemiologic approach via inbred mouse strain crosses was used to map genes that modify an individual's risk of heart defects caused by an Nkx2-5 mutation.

TL;DR: This review addresses immunologic concepts and clinical lessons learned from heart valve replacement using xenogeneic tissues, the advancement of xenotransplantation using organs from genetically modified animals, and the progression of this research to the first-in-man pig-to-human heart transplantation.

TL;DR: The aim of this protocol is to provide a reproducible and robust approach for achieving ex vivo delivery of a therapeutic to the entire cardiac allograft prior to transplantation and provide technical details to perform a survival heterotopic transplant of the ex vivo perfused heart.

TL;DR: In this paper , a review of tissue-engineered heart valves and partial heart transplantation as potential growing heart valve implants in large animal and clinical translational research is presented, as well as the barriers to clinical translation.