Linda J. Porrino

TL;DR: The widespread cortical targets of MD neurons together with evidence for multiple thalamic inputs to prefrontal areas support a revision of the classical hodological definition of prefrontal cortex as the exclusive cortical recipient of MD projections.

TL;DR: In this article, a single dose of the indirect-acting dopa-minergic agonist cocaine increases multiple Fos proteins in rat caudate nucleus and the increase is dose-dependent and is immunocytochemically at 1 hr, maximal at 2 hr, and absent 48 hr after treatment.

TL;DR: It is reported that the acute administration of a single dose of the indirect-acting dopaminergic agonist cocaine increases multiple Fos proteins in rat caudate nucleus and this data indicate that D1 dopamine receptors are linked to a cellular immediate-early gene system(s) and suggest an action of cocaine at one or more levels of gene expression via modulation of transcriptional processes in activated cells.

TL;DR: The isotope injection of the amygdala revealed a projection to the magnocellular moeity of the mediodorsal nucleus (MDmc) which is known to innervate the same ventromedial regions of the frontal lobe that receive direct connections from the amygdala.

TL;DR: In this article, the authors found that the mechanism of recovery of parkinsonian primates after implantation of fetal mesencephalon tissue into the caudate nucleus is by stimulation of sprouting from host neurons.