Lingfeng Lai

TL;DR: It is demonstrated that intravenous transplantation of MSCs decreased the levels of ONOO− and degree of BBB leakage and improved neurological recovery in a rat ICH model, which may provide a new insight for future therapies that aim to prevent breakdown of the BBB in patients with ICH.

TL;DR: AVM size and deep venous drainage were independently associated with hemorrhage in pediatric patients, and complete embolization can be achieved in small AVMs, while large AVMs can be adequately reduced in size for additional microsurgery or stereotactic radiosurgery.

TL;DR: The results suggest that baicalein exerts a protective effect on BBB disruption in the rat model of ICH, via inhibition of MAPKs and NF-κB signaling pathways, leading to decreased formation of iNOS and ONOO−, thereby improving neurological function.

TL;DR: Endovascular coiling of unruptured intracranial aneurysms resulted in relief of headache in most of the elderly patients, and a preoperative headache score was the only statistically significant predictor of headache outcome.

TL;DR: Use of the stent-assisted neck remodelling technique in the treatment of wide-necked posterior communicating artery intracranial aneurysms appears to improve the long-term clinical outcome.