L
Liquan Zhu
Researcher at Zhejiang University of Technology
Publications - 15
Citations - 92
Liquan Zhu is an academic researcher from Zhejiang University of Technology. The author has contributed to research in topics: Medicine & Computer science. The author has an hindex of 2, co-authored 2 publications receiving 40 citations.
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A red-emitting fluorescent probe for mitochondria-target microviscosity in living cells and blood viscosity detection in hyperglycemia mice
TL;DR: A new red-emitting viscosity sensor NV constructed by linking naphthalimide and benzo[e]indolium via a C–C double bond displayed strong fluorescence emission at 635 nm in highly-viscous medium, and exhibited two-fold fluorescence enhancement in the fresh blood of hyperglycemia mice over that of normal mice.
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A dual functional fluorogenic probe for visualization of intracellular pH and formaldehyde with distinct fluorescence signals
TL;DR: A single fluorescent probe (DPFP) containing a 1,8-naphthalimide dye and a homoallylamino group for imaging pH and formaldehyde has been developed that exhibits significant blue fluorescence under acidic pH conditions and green fluorescence in the presence of FA.
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Recent advances in the development of EGFR degraders: PROTACs and LYTACs.
TL;DR: In this paper , the structural properties of EGFR, the inhibitors that have been developed against WT/mutated EGFR and then mainly focuses on the recent advances of EGfr-targeting degraders along with its limitations and unlimited prospects.
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Fluorogenic and Mitochondria-Localizable Probe Enables Selective Labeling and Imaging of Nitroreductase.
TL;DR: Compared with conventional fluorescent probes, this new NTR probe not only offers mitochondrial localizable and fluorogenic response but also achieves permanent retention on the site of activation with an enhanced spatial resolution to improve the detection sensitivity even after cell fixation.
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Cell-penetrating poly(disulfide)-based nanoquenchers (qCPDs) for self-monitoring of intracellular gene delivery.
Wenjie Lang,Si Si Liew,Shuyi Wang,Dawei Hong,Liquan Zhu,Shubo Du,Linye Jiang,Shao Q. Yao,Jingyan Ge +8 more
TL;DR: A nanoquencher system by doping a FRET pair during nucleic acid-assisted cell penetrating poly(disulfide) (CPD) formation produces an efficient gene delivery polymer with minimal endolysosomal trapping, but also enables monitoring the release of the gene from the vehicle in live cells.