Liqun Lu

TL;DR: A review of research progress on AHPND is hoped to serve as a useful introduction for researchers who are currently unfamiliar with the disease, but have backgrounds in bacterial virulence, detection, and epidemiology, and may be encouraged to participate in the research effort to reduce AHP ND’s impact on shrimp cultivation.

TL;DR: In situ hybridization analysis indicated that there was extensive viral replication and lysis in the kidneys of moribund fish, in contrast to very limited replication in surviving fish, and significantly upregulated immune-related genes identified can serve as candidate marker genes for acute CyHV-2 infection.

TL;DR: To validate the hypothesis that both viruses might co-infect grass carp without significant interference in the field, clinical samples from two different fish farms in 2012 were collected and virus loads for each fish were monitored and demonstrated that, although GCRV-JX02 did reduce the cellular replication level of GCRVs up to 10-fold during co- Infection, there was no significant impact on the productive virus progeny level in supernatant compared to that of cells infected by G CRV-

TL;DR: The present study suggested that the multiple miRNAs, displaying diverse kinetics and tissue sources on antibacterial immune processes, should be considered a major focus for future research.

TL;DR: The present study showed that the viral VP5 protein was involved in viral infection and bacterially-expressed VP5 could be suitable for developing subunit vaccine for the control of GCRV infection.