L
Lisandro Pacheco-Lugo
Researcher at Simón Bolívar University
Publications - 12
Citations - 218
Lisandro Pacheco-Lugo is an academic researcher from Simón Bolívar University. The author has contributed to research in topics: Gene & Trypanosoma cruzi. The author has an hindex of 6, co-authored 10 publications receiving 164 citations. Previous affiliations of Lisandro Pacheco-Lugo include Federal University of Paraná & Universidad del Norte, Colombia.
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Journal ArticleDOI
Cholesterol-Rich Microdomains as Docking Platforms for Respiratory Syncytial Virus in Normal Human Bronchial Epithelial Cells
Homero San-Juan-Vergara,Homero San-Juan-Vergara,Viviana Sampayo-Escobar,Niradiz Reyes,Byeong J. Cha,Lisandro Pacheco-Lugo,Lisandro Pacheco-Lugo,Terianne Wong,Mark E. Peeples,Mark E. Peeples,Peter L. Collins,Maria Eugenia Castaño,Shyam S. Mohapatra +12 more
TL;DR: RSV entry appears that RSV entry depends on its ability to dock to cholesterol-rich microdomains in the plasma membrane where hemifusion events begin, assisted by a Pak1-dependent process.
Journal ArticleDOI
Profiling analysis of circulating microRNA in peripheral blood of patients with class IV lupus nephritis.
Elkin Navarro-Quiroz,Lisandro Pacheco-Lugo,Roberto Navarro-Quiroz,Hernan Lorenzi,Pierine España-Puccini,Yirys Díaz-Olmos,Lisneth Almendrales,Valeria Olave,Henry González-Torres,Anderson Díaz-Pérez,Alex Dominguez,Antonio Iglesias,Raul García,Gustavo Aroca-Martínez +13 more
TL;DR: Evaluating the relative abundance of circulating microRNAs in peripheral blood from Colombian patients with LN-IV found changes in the abundance could be interpreted as alterations in the miRNAs-mRNA regulatory network in the pathogenesis of LN, preceding the clinical onset of the disease.
Journal ArticleDOI
High-Throughput Sequencing Reveals Circulating miRNAs as Potential Biomarkers of Kidney Damage in Patients with Systemic Lupus Erythematosus.
Elkin Navarro-Quiroz,Lisandro Pacheco-Lugo,Hernan Lorenzi,Yirys Díaz-Olmos,Lisneth Almendrales,Edwin Rico,Roberto Mota Navarro,Pierine España-Puccini,Antonio Iglesias,Eduardo Egea,Gustavo Aroca +10 more
TL;DR: Changes in the abundance of miRNAs in plasma samples from patients with lupus nephritis that could potentially allow the diagnosis of renal damage in SLE patients are identified.
Journal ArticleDOI
Plasma cytokines as potential biomarkers of kidney damage in patients with systemic lupus erythematosus.
Lisandro Pacheco-Lugo,J Sáenz-García,E. Navarro quiroz,H González Torres,Luis Fang,Yirys Díaz-Olmos,G Garavito de Egea,Eduardo Egea Bermejo,G Aroca Martínez +8 more
TL;DR: The data indicate that circulating cytokines and chemokines could be considered good predictors of renal involvement in individuals with systemic lupus erythematosus.
Journal ArticleDOI
Effective gene delivery to Trypanosoma cruzi epimastigotes through nucleofection.
Lisandro Pacheco-Lugo,Yirys Díaz-Olmos,José L. Sáenz-Garcia,Christian Probst,Wanderson D. DaRocha +4 more
TL;DR: The small amount of epimastigotes and DNA required for the nucleofection can turn the method adopted here into an attractive tool for high throughput screening (HTS) applications, and for gene editing in parasites where genetic manipulation tools remain relatively scarce.