L
Liudmyla Drobot
Researcher at National Academy of Sciences of Ukraine
Publications - 8
Citations - 54
Liudmyla Drobot is an academic researcher from National Academy of Sciences of Ukraine. The author has contributed to research in topics: Lewis lung carcinoma & Jurkat cells. The author has an hindex of 3, co-authored 8 publications receiving 34 citations.
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Journal ArticleDOI
Toxicity of C 60 fullerene-cisplatin nanocomplex against Lewis lung carcinoma cells.
Svitlana Prylutska,I. I. Grynyuk,T. D. Skaterna,Iryna Horak,Anna Grebinyk,Anna Grebinyk,Liudmyla Drobot,O. P. Matyshevska,A. Senenko,Yuriy Prylutskyy,A.G. Naumovets,Uwe Ritter,Marcus Frohme +12 more
TL;DR: Toxic effects of the nanocomplex formed by noncovalent interaction of C60 fullerene with Cis-Pt against Lewis lung carcinoma (LLC) cells in comparison with free drug are estimated.
Journal Article
Apoptosis photoinduction by C60 fullerene in human leukemic T cells.
K O Palyvoda,I. I. Grynyuk,Svitlana Prylutska,A A Samoylenko,Liudmyla Drobot,O. P. Matyshevska +5 more
TL;DR: The viability of normal (Wistar rat thymocytes) and transformed T cells after UV/Vis irradiation in the presence of pristine C60 fullerene was studied and may be useful for development of photosensitizers for photodynamic therapy with selective action on leukemia cells.
Journal ArticleDOI
Antitumor efficiency of the natural alkaloid berberine complexed with C60 fullerene in Lewis lung carcinoma in vitro and in vivo
Anna Grebinyk,Svitlana Prylutska,Sergii Grebinyk,Maxim P. Evstigneev,Iryna Krysiuk,T. D. Skaterna,Iryna Horak,Yanfang Sun,Liudmyla Drobot,O. P. Matyshevska,Yuriy Prylutskyy,Uwe Ritter,Marcus Frohme +12 more
TL;DR: In this article, C60-Ber noncovalent nanocomplexes were synthesized in 1:2, 1:1 and 2:1 molar ratios for Lewis lung carcinoma (LLC).
Journal Article
Photoactivated fullerene C60 induces store-operated Ca2 entry and cytochrome c release in Jurkat cells.
Sergii Grebinyk,K O Palyvoda,Svitlana Prylutska,Grynyuk,A A Samoylenko,Liudmyla Drobot,O. P. Matyshevska +6 more
TL;DR: It is supposed that Ca2+ flux remodulation induced by photoexcited fullerene C60 in Jurkat cells might be involved in the initiation of signalling events leading to cell apoptosis.
Journal ArticleDOI
Mode of photoexcited C60 fullerene involvement in potentiating cisplatin toxicity against drug-resistant L1210 cells.
Franskevych Dv,Svitlana Prylutska,I. I. Grynyuk,Ganna Pasichnyk,Liudmyla Drobot,O. P. Matyshevska,O. P. Matyshevska,Uwe Ritter +7 more
TL;DR: The effect of the synergic cytotoxic activity of both agents allowed to suppose that photoexcited C60 fullerene promoted Cis-Pt accumulation in leukemic cells resistant to Cis -Pt.