L
Liya Zhu
Researcher at Kyungpook National University
Publications - 22
Citations - 1197
Liya Zhu is an academic researcher from Kyungpook National University. The author has contributed to research in topics: Mesenchymal stem cell & In vivo. The author has an hindex of 14, co-authored 21 publications receiving 713 citations. Previous affiliations of Liya Zhu include Kyungpook National University Hospital.
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Journal ArticleDOI
Exosomes Derived From Natural Killer Cells Exert Therapeutic Effect in Melanoma.
Liya Zhu,Senthilkumar Kalimuthu,Prakash Gangadaran,Ji Min Oh,Ho-Won Lee,Se Hwan Baek,Shin Young Jeong,Sang-Woo Lee,Jaetae Lee,Byeong-Cheol Ahn +9 more
TL;DR: In this paper, the authors explored NK cell-derived exosome-mediated antitumor effects against aggressive melanoma in vitro and in vivo, and the results indicated that exosomes derived from NK cells exert cytotoxic effects on melanoma cells.
Journal ArticleDOI
A New Approach for Loading Anticancer Drugs Into Mesenchymal Stem Cell-Derived Exosome Mimetics for Cancer Therapy.
Senthilkumar Kalimuthu,Senthilkumar Kalimuthu,Prakash Gangadaran,Prakash Gangadaran,Ramya Lakshmi Rajendran,Ramya Lakshmi Rajendran,Liya Zhu,Liya Zhu,Ji Min Oh,Ji Min Oh,Ho-Won Lee,Ho-Won Lee,Arunnehru Gopal,Arunnehru Gopal,Se Hwan Baek,Se Hwan Baek,Shin Young Jeong,Shin Young Jeong,Sang-Woo Lee,Sang-Woo Lee,Jaetae Lee,Jaetae Lee,Byeong-Cheol Ahn,Byeong-Cheol Ahn +23 more
TL;DR: MSC-EMs were successfully isolated using simple procedures and drug-loaded MSC- EMs were shown to be therapeutically efficient for the treatment of breast cancer both in vitro and in vivo.
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Extracellular vesicles derived from MSCs activates dermal papilla cell in vitro and promotes hair follicle conversion from telogen to anagen in mice
Ramya Lakshmi Rajendran,Prakash Gangadaran,Soon Sun Bak,Ji Min Oh,Senthilkumar Kalimuthu,Ho Won Lee,Se Hwan Baek,Liya Zhu,Young Kwan Sung,Shin Young Jeong,Sang-Woo Lee,Jaetae Lee,Byeong-Cheol Ahn +12 more
TL;DR: For the first time, results suggest that MSC-EVs have a potential to activate DP cells, prolonged survival, induce growth factor activation in vitro, and promotes hair growth in vivo.
Journal ArticleDOI
In Vivo Tracking of Chemokine Receptor CXCR4-Engineered Mesenchymal Stem Cell Migration by Optical Molecular Imaging.
Senthilkumar Kalimuthu,Ji Min Oh,Prakash Gangadaran,Liya Zhu,Ho Won Lee,Ramya Lakshmi Rajendran,Se Hwan Baek,Yong Hyun Jeon,Shin Young Jeong,Sang-Woo Lee,Jaetae Lee,Byeong-Cheol Ahn +11 more
TL;DR: Intravenous delivery of genetically modified MSCs overexpressing CXCR4 with a Fluc2 reporter gene may be a useful, noninvasive BLI imaging tool for tracking cell fate.
Journal ArticleDOI
A new bioluminescent reporter system to study the biodistribution of systematically injected tumor-derived bioluminescent extracellular vesicles in mice
Prakash Gangadaran,Xiu Juan Li,Ho Won Lee,Ji Min Oh,Senthilkumar Kalimuthu,Ramya Lakshmi Rajendran,Seung Hyun Son,Se Hwan Baek,Thoudam Debraj Singh,Thoudam Debraj Singh,Liya Zhu,Shin Young Jeong,Sang-Woo Lee,Jaetae Lee,Byeong-Cheol Ahn +14 more
TL;DR: In vivo bioluminescence imaging using Renilla luciferase (Rluc) was developed and applied to monitoring of EVs derived from thyroid cancer and breast cancer in nude mice after intravenous administration and was compared with a dye-based labeling method for EV derived from CAL-62 cells.