L
Londale Madrigal
Researcher at University of Aberdeen
Publications - 3
Citations - 57
Londale Madrigal is an academic researcher from University of Aberdeen. The author has contributed to research in topics: Methylenetetrahydrofolate reductase & Metatarsal bones. The author has an hindex of 3, co-authored 3 publications receiving 53 citations.
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Journal ArticleDOI
The C677T Polymorphism in the Methylenetetrahydrofolate Reductase Gene (MTHFR), Maternal Use of Folic Acid Supplements, and Risk of Isolated Clubfoot: A Case-Parent-Triad Analysis
Linda Sharp,Z. Miedzybrodzka,A. H. Cardy,Julie Anne Inglis,Londale Madrigal,Simon Barker,David Chesney,Caroline Clark,Nicola Maffulli +8 more
TL;DR: This is the first known report of a specific genetic polymorphism associated with clubfoot, and the direction of the association is intriguing and suggests that DNA synthesis may be relevant in clubfoot development.
The c677t polymorphism in the methylenetetrahydrofolate reductase gene (mthfr), maternal use of folic acid supplements and risk of isolated clubfoot: a caseparent triad analysis
Nicola Maffulli,Linda Sharp,Z Miedzybrodzka,A. H. Cardy,Julie Anne Inglis,Londale Madrigal,S Barker,D Chesney,C Clark +8 more
TL;DR: In this paper, the authors investigated whether the MTHFR C677T polymorphism, and maternal peri-conceptional folic acid supplement use, influenced risk of isolated clubfoot.
Journal ArticleDOI
Micro-magnetic resonance imaging and embryological analysis of wild-type and pma mutant mice with clubfoot
S. L. Duce,Londale Madrigal,Katy Schmidt,Craig Cunningham,Guoqing Liu,Simon Barker,Gordon Tennant,Cheryll Tickle,Sandy Chudek,Z. Miedzybrodzka +9 more
TL;DR: If the usefulness of the pma mutant as a model is confirmed, then these findings on pma mouse embryos, when extrapolated to humans, would support a long‐standing hypothesis that CTEV is due to the failure of completion of the normal process of rotation and angulation.