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Loredana Costabile

Researcher at University of Perugia

Publications -  11
Citations -  521

Loredana Costabile is an academic researcher from University of Perugia. The author has contributed to research in topics: Luteal phase & Embryo transfer. The author has an hindex of 10, co-authored 11 publications receiving 489 citations.

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Endometrial effects of long-term treatment with phytoestrogens: a randomized, double-blind, placebo-controlled study.

TL;DR: Long-term treatment (up to 5 years) with soy phytoestrogens was associated with an increased occurrence of endometrial hyperplasia, calling into question the long-term safety of phy toestrogens with regard to the endometrium.
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Phytoestrogens may improve the pregnancy rate in in vitro fertilization-embryo transfer cycles: a prospective, controlled, randomized trial.

TL;DR: Although the results of this study encourage the use of phytoestrogens for luteal phase support in patients undergoing IVF-ET program, more studies are necessary to support the hypothesis that phy toestrogens have a beneficial effect in IVF cycles.
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Recombinant versus urinary follicle-stimulating hormone in intrauterine insemination cycles: A prospective, randomized analysis of cost effectiveness

TL;DR: Urinary FSH and recombinant FSH are both effective in ovarian stimulation in IUI cycles and the urinary preparation is more cost effective due to the difference of its cost per IU.
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A prospective randomized study comparing intramuscular progesterone and 17α-hydroxyprogesterone caproate in patients undergoing in vitro fertilization–embryo transfer cycles

TL;DR: Although the results of the study encourage the use of 17-HPC for luteal phase support in patients undergoing IVF-ET program, more studies are necessary to support the hypothesis that it can replace i.m. P-in-oil.
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Low dose of ethinyl estradiol can reverse the antiestrogenic effects of clomiphene citrate on endometrium.

TL;DR: It is shown that CC has a deleterious effect on endometrium maturity and that adding ethinyl-E2 produces a favorable endometrial response even with very low doses.