L
Lori D. Hill
Researcher at Virginia Commonwealth University
Publications - 8
Citations - 292
Lori D. Hill is an academic researcher from Virginia Commonwealth University. The author has contributed to research in topics: Population & Single-nucleotide polymorphism. The author has an hindex of 5, co-authored 8 publications receiving 265 citations. Previous affiliations of Lori D. Hill include VCU Medical Center.
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Journal ArticleDOI
Connective tissue and related disorders and preterm birth: clues to genes contributing to prematurity.
TL;DR: In this article, the authors examined the existing literature on the association between known disorders of connective tissue synthesis and metabolism and related diseases and prematurity, and identified gene mutations inherited by the fetus that could predispose to preterm birth as a result of PPROM.
Journal ArticleDOI
Fetal ERAP2 variation is associated with preeclampsia in African Americans in a case-control study.
Lori D. Hill,DaShaunda D. Hilliard,Timothy P. York,Sindhu K. Srinivas,Juan Pedro Kusanovic,Juan Pedro Kusanovic,Ricardo Gomez,Michal A. Elovitz,Roberto Romero,Jerome F. Strauss +9 more
TL;DR: An association between fetal ERAP2 and preeclampsia in an African American population is reported, providing strong evidence that ERAP 2 plays a role in the development of preeclampia.
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Epistasis between COMT and MTHFR in maternal-fetal dyads increases risk for preeclampsia.
Lori D. Hill,Timothy P. York,Juan Pedro Kusanovic,Juan Pedro Kusanovic,Ricardo Gomez,Lindon J. Eaves,Roberto Romero,Jerome F. Strauss +7 more
TL;DR: A role for both maternal and fetal COMT in preeclampsia is demonstrated and the importance of including allelic variation in MTHFR is highlighted, which is linked to enzyme activity and four single nucleotide polymorphisms that characterize COMT activity.
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A novel ERAP2 haplotype structure in a Chilean population: implications for ERAP2 protein expression and preeclampsia risk
Derek L. Vanhille,Lori D. Hill,DaShaunda D. Hilliard,Eun D. Lee,Maria E. Teves,Sindhu K. Srinivas,Juan Pedro Kusanovic,Juan Pedro Kusanovic,Ricardo Gomez,Efstratios Stratikos,Michal A. Elovitz,Roberto Romero,Jerome F. Strauss +12 more
TL;DR: It is concluded that the Chilean ERAP2 haplotype structure allows for the expression of the major T allele of rs2549782 encoding 392N, which could impact peptide trimming and antigen presentation, which reveals heretofore unrecognized complexity of the ERAP 2 locus.
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Is laminin gamma-1 a candidate gene for advanced pelvic organ prolapse?
TL;DR: While significant differences were identified between AA and Caucasian women, no associations were found between any LAMC1 gene variant and advanced POP.