L
Louise E. McDonald
Researcher at Royal Prince Alfred Hospital
Publications - 1
Citations - 3183
Louise E. McDonald is an academic researcher from Royal Prince Alfred Hospital. The author has contributed to research in topics: Methylated DNA immunoprecipitation & Illumina Methylation Assay. The author has an hindex of 1, co-authored 1 publications receiving 3021 citations.
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A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands.
Marianne Frommer,Louise E. McDonald,Douglas Spencer Millar,Christina M. Collis,Fujiko Watt,Geoffrey W. Grigg,Peter L. Molloy,Cheryl L. Paul +7 more
TL;DR: A genomic sequencing method is reported that provides positive identification of 5-methylcytosine residues and yields strand-specific sequences of individual molecules in genomic DNA, which suggests that the high methylation level of single-copy sequences in sperm may be locally modulated by binding of protein factors in germ-line cells.