L
Lucía Margarita Valenzuela-Salas
Researcher at Autonomous University of Baja California
Publications - 3
Citations - 48
Lucía Margarita Valenzuela-Salas is an academic researcher from Autonomous University of Baja California. The author has contributed to research in topics: Lethal dose & Cisplatin. The author has an hindex of 2, co-authored 3 publications receiving 26 citations.
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Journal ArticleDOI
Antiproliferative and Antitumour Effect of Nongenotoxic Silver Nanoparticles on Melanoma Models.
Lucía Margarita Valenzuela-Salas,Nayeli G. Girón-Vázquez,Juan Carlos García-Ramos,Olivia Torres-Bugarín,Claudia M. Gómez,Alexey Pestryakov,Luis Jesús Villarreal-Gómez,Yanis Toledano-Magaña,Nina Bogdanchikova +8 more
TL;DR: The results exhibit the remarkable antitumour activity of a nongenotoxic AgNP formulation and constitute the first advance toward the application of these AgNPs for melanoma treatment, which could considerably reduce adverse effects provoked by currently applied chemotherapeutics.
Journal ArticleDOI
Antitumor Activity against Human Colorectal Adenocarcinoma of Silver Nanoparticles: Influence of [Ag]/[PVP] Ratio.
Omar Ulises Cruz-Ramírez,Lucía Margarita Valenzuela-Salas,Alberto Blanco-Salazar,José Antonio Rodríguez-Arenas,Paris Astrid Mier-Maldonado,Juan Carlos García-Ramos,Nina Bogdanchikova,Alexey Pestryakov,Yanis Toledano-Magaña +8 more
TL;DR: In this paper, the authors report the complete characterization of five polyvinylpyrrolidone-coated AgNP (PVP-AgNP) formulations, their cytotoxic activity against human colon tumor cells (HCT-15), their effect on primary mouse cultures, and their lethal dose on BALB/c mice.
Journal ArticleDOI
New Protein-Coated Silver Nanoparticles: Characterization, Antitumor and Amoebicidal Activity, Antiproliferative Selectivity, Genotoxicity, and Biocompatibility Evaluation.
Lucía Margarita Valenzuela-Salas,Alberto Blanco-Salazar,Jesús David Perrusquía-Hernández,Mario Nequiz-Avendaño,Paris Astrid Mier-Maldonado,Balam Ruiz-Ruiz,Verónica Campos-Gallegos,María Evarista Arellano-García,Juan Carlos García-Ramos,Alexey Pestryakov,Luis Jesús Villarreal-Gómez,Yanis Toledano-Magaña,Nina Bogdanchikova +12 more
TL;DR: All results from toxicological evaluation suggest a Category 5 (practically nontoxic) of the Globally Harmonized System of Classification and Labelling of Chemicals for that protein-coated AgNPs formulation after oral administration for a short period and urge the completion of its preclinical toxicological profile.