I have developed "tennis elbow" from lugging this book around the past four weeks, but it is worth the pain, the effort, and the aspirin. It is also worth the (relatively speaking) bargain price. Including appendixes, this book contains 894 pages of text. The entire panorama of the neural sciences is surveyed and examined, and it is comprehensive in its scope, from genomes to social behaviors. The editors explicitly state that the book is designed as "an introductory text for students of biology, behavior, and medicine," but it is hard to imagine any audience, interested in any fragment of neuroscience at any level of sophistication, that would not enjoy this book. The editors have done a masterful job of weaving together the biologic, the behavioral, and the clinical sciences into a single tapestry in which everyone from the molecular biologist to the practicing psychiatrist can find and appreciate his or

Principles of Neural Science

The sustainability of aquaculture has been debated intensely since 2000, when a review on the net contribution of aquaculture to world fish supplies was published in Nature. This paper reviews the developments in global aquaculture from 1997 to 2017, incorporating all industry sub-sectors and highlighting the integration of aquaculture in the global food system. Inland aquaculture—especially in Asia—has contributed the most to global production volumes and food security. Major gains have also occurred in aquaculture feed efficiency and fish nutrition, lowering the fish-in–fish-out ratio for all fed species, although the dependence on marine ingredients persists and reliance on terrestrial ingredients has increased. The culture of both molluscs and seaweed is increasingly recognized for its ecosystem services; however, the quantification, valuation, and market development of these services remain rare. The potential for molluscs and seaweed to support global nutritional security is underexploited. Management of pathogens, parasites, and pests remains a sustainability challenge industry-wide, and the effects of climate change on aquaculture remain uncertain and difficult to validate. Pressure on the aquaculture industry to embrace comprehensive sustainability measures during this 20-year period have improved the governance, technology, siting, and management in many cases. The volume of global aquaculture production has tripled since 2000 with positive trends in environmental performance, but the sector faces mounting challenges including pathogen management, pollution, climate change, and increasing dependence on land-based resource systems.

/pdf/a-20-year-retrospective-review-of-global-aquaculture-348juu7y75.pdf

A 20-year retrospective review of global aquaculture.

Seismic Rehabilitation of Existing Buildings

Neuroimmunology of Traumatic Brain Injury: Time for a Paradigm Shift.

Emerging artificial intelligence methods in structural engineering

The paper details two monitoring systems implemented in the main nave of Santa Maria of Belem Church of the Monastery of Jeronimos, in Lisbon. The monitoring systems were installed to better understand the static and dynamic behavior of the structure, aiming at the damage detection and the improvement of seismic resistance of the monument. Preliminary investigations, numerical non-linear analyses and the first dynamic modal identification analyses are described in the paper. Also the preliminary works for the monitoring systems are presented, including the points selected for observation, discussion of the sensors technical characteristics, as well as preliminary inspection and diagnosis. The first results of the dynamic monitoring system are shown and the future developments on the systems are presented, aiming at a full integration of all the adopted techniques.

/pdf/structural-monitoring-of-the-monastery-of-jeronimos-2eoucnv5we.pdf

Structural monitoring of the Monastery of Jerónimos

Objective: Apoptosis increases in traumatic brain injury (TBI). Caspase-cleaved cytokeratin (CCCK)-18 in blood during apoptosis could appear. At the time of admission due to TBI, higher blood CCCK-18 levels were found in non-surviving than in surviving patients. Therefore, the objective of our study was to analyze whether serum CCCK-18 levels determined during the first week after TBI could predict early mortality (at 30 days). Methods: Severe TBI patients were included (considering severe when Glasgow Coma Scale < 9) in this observational and multicentre study. Serum CCCK-18 levels were determined at day 1 of TBI, and at days 4 and 8 after TBI. Results: Serum CCCK-18 levels at day 1 of TBI, and in the days 4 and 8 after TBI were higher (p < 0.001) in non-surviving than in surviving patients (34 and 90 patients, respectively) and could predict early mortality (p < 0.001 in the area under the curve). Conclusions: The new findings from our study were that serum CCCK-18 levels at any moment of the first week of TBI were higher in non-surviving patients and were able to predict early mortality.

https://www.mdpi.com/2076-3425/9/10/269/pdf

High Serum Caspase-Cleaved Cytokeratin-18 Levels and Mortality of Traumatic Brain Injury Patients

Dynamic Identification and Modal Updating of S. Torcato Church

Traditional buildings basically include natural and autochthonous construction materials and are built with sustainable construction techniques. The knowledge of these materials’s state and construction techniques is required for a proper conservation/renovation work. It is well known that the lack of maintenance is one of the main causes that contribute to the high degree of degradation that the Portuguese traditional buildings unfortunately have. That degradation may even compromise the overall structural integrity of the building thus reducing its lifetime`s expectation. Meanwhile, a partial or even full demolition of a building is still an often occurrence in the Portuguese context. From a sustainable and building heritage perspectives that practise may be inadequate. Taking into account that generally the degradation problems are linked with roof`s leaking anomalies and that the structural components of the roof tend to be the first ones to be affected, this timber structural roof components of Portuguese dwellings were the object of the research work here presented.

/pdf/aging-effect-on-the-integrity-of-traditional-portuguese-1apl0kf113.pdf

Luís F. Ramos

Papers

Structural monitoring of the Monastery of Jerónimos

High Serum Caspase-Cleaved Cytokeratin-18 Levels and Mortality of Traumatic Brain Injury Patients

Dynamic Identification and Modal Updating of S. Torcato Church

Aging effect on the integrity of traditional portuguese timber roof structures

High serum substance P levels and mortality after malignant middle cerebral artery infarction