Showing papers by "Luis M. Ruilope published in 1978"

Renal vein thrombosis, nephrotic syndrome, and focal lupus glomerulonephritis.

Abstract: Formerly intramuscular injection ofvasopressin tannate in oil provided a useful and convenient means of assessing urine concentrating ability,' although it was a less potent stimulus than fluid deprivation.' Because vasopressin tannate in oil is now no longer manufactured another practical test of concentrating ability must be defined. We describe an investigation of the use of 1-diamino,8-D-arginine vasopressin, desmopressin (DDAVP, Ferring Pharmaceuticals Ltd), by intramuscular (IM) and intranasal (IN) administration to test urine concentrating ability in adults, firstly in an overnight test and then in a shorter day test using only IN desmopressin. The desmopressin day test is simpler and as useful as the conventional overnight vasopressin test.

Aldosterone regulation in anephric patients.

Abstract: The response of plasma aldosterone to hemodialysis, 3 h orthostatism, K-loading and angiotensin II and ACTH infusions has been studied. Hemodialysis, orthostatism and angiotensin II infusion do not modify aldosterone levels. By the contrary ACTH and potassium originate a significant increase in plasma aldosterone. They seem to be the main aldosterone secretion regulators in the absence of renin production.