L
Luiz José de Souza
Researcher at Oswaldo Cruz Foundation
Publications - 35
Citations - 934
Luiz José de Souza is an academic researcher from Oswaldo Cruz Foundation. The author has contributed to research in topics: Dengue fever & Dengue virus. The author has an hindex of 14, co-authored 31 publications receiving 807 citations.
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Journal ArticleDOI
Aminotransferase changes and acute hepatitis in patients with dengue fever: analysis of 1,585 cases
Luiz José de Souza,José Galvão Alves,Rita Maria Ribeiro Nogueira,Carlos Gicovate Neto,Diogo Assed Bastos,Edno Wallace da Silva Siqueira,João Tadeu Damian Souto Filho,Thiago de Abreu Cezário,Carlos Eduardo C. Soares,Rodrigo da Costa Carneiro +9 more
TL;DR: Liver damage with elevation of aminotransferases and reactive hepatitis was a common complication of dengue virus infection in these patients.
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Dengue virus type 3, Brazil, 2002.
Rita Maria Ribeiro Nogueira,Hermann Gonçalves Schatzmayr,Ana Maria Bispo de Filippis,Flavia Barreto dos Santos,Rivaldo Venâncio da Cunha,Janice Coelho,Luiz José de Souza,Flávia Ramos Guimarães,Eliane Saraiva Machado de Araújo,Thatiane Santos De Simone,Meri Baran,Gualberto Teixeira,Marize Pereira Miagostovich +12 more
TL;DR: An explosive epidemic of DENV-3 in 2002 was the most severe d Dengue epidemic reported in Brazil since dengue viruses were introduced.
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The impact of dengue on liver function as evaluated by aminotransferase levels
Luiz José de Souza,Rita Maria Ribeiro Nogueira,Leandro Cordeiro Soares,Carlos Eduardo C. Soares,Bruno Fernandes Ribas,Felipe Pinto Alves,Fabíola Rodrigues Vieira,Felipe Eulálio Baldi Pessanha +7 more
TL;DR: Liver damage is a common complication of dengue infection and aminotransferase levels are a valuable marker for monitoring these cases, and they were measured according to two MAC-ELISA protocols.
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Dengue Virus Activates Membrane TRAIL Relocalization and IFN-α Production by Human Plasmacytoid Dendritic Cells In Vitro and In Vivo
Mariana Gandini,Christophe Gras,Elzinandes Leal de Azeredo,Luzia Maria de Oliveira Pinto,Nikaïa Smith,Philippe Desprès,Rivaldo Venâncio da Cunha,Luiz José de Souza,Claire Fernandes Kubelka,Jean-Philippe Herbeuval +9 more
TL;DR: This investigation characterizes, during DENV-2 infection, activation of pDCs in vivo and their antiviral role in vitro, and proposes TRAIL-expressing p DCs may have an important role in the outcome of disease.
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Regulation of inflammatory chemokine receptors on blood T cells associated to the circulating versus liver chemokines in dengue fever.
Luzia Maria de-Oliveira-Pinto,Cintia Ferreira Marinho,Tiago F. Póvoa,Elzinandes Leal de Azeredo,Luiza Assed de Souza,Luiza Damian Ribeiro Barbosa,Ana Rita Coimbra Motta-Castro,Ada M. B. Alves,Carlos Avila,Luiz José de Souza,Rivaldo Venâncio da Cunha,Paulo Vieira Damasco,Marciano Viana Paes,Claire Fernandes Kubelka +13 more
TL;DR: Liver from dengue fatal patients showed increased number of cells expressing CCL5/RANTES in three out of four cases compared to three death from a non-dengue patient, bolstering a hypothesis that the CCR5 expression would be promoting an enhanced T cell recruitment into liver.