L
Lumonadio Luyengi
Researcher at University of Illinois at Chicago
Publications - 15
Citations - 1452
Lumonadio Luyengi is an academic researcher from University of Illinois at Chicago. The author has contributed to research in topics: Ornithine decarboxylase & Cerbera manghas. The author has an hindex of 13, co-authored 15 publications receiving 1363 citations.
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Journal Article
Evaluation of the antioxidant potential of natural products.
Sang Kook Lee,Z H Mbwambo,Chung Hs,Lumonadio Luyengi,E. J. C. Gamez,Rajendra G. Mehta,A. D. Kinghorn,John M. Pezzuto +7 more
TL;DR: Of these substances, the hydroxystilbenes piceatannol and transresveratrol have thus far been shown to inhibit carcinogen-induced preneoplastic lesion formation in the mouse mammary gland organ culture model.
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Rotenoids mediate potent cancer chemopreventive activity through transcriptional regulation of ornithine decarboxylase.
Clarissa Gerhäuser,W. Mar,W. Mar,Sang Kook Lee,Nanjoo Suh,Y. Luo,Jerome W. Kosmeder,Lumonadio Luyengi,Harry H. S. Fong,A D Kinghorn,Robert M. Moriarty +10 more
TL;DR: Four active rotenoids obtained from the African plant Mundulea sericea were obtained and appear to function by a unique mechanism at the level of ODC messenger RNA expression, which can be regarded as promising new chemopreventive or anticancer agents.
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Dose-dependent production of mammalian lignans in rats and in vitro from the purified precursor secoisolariciresinol diglycoside in flaxseed.
Sharon E. Rickard,Lindy J. Orcheson,Maja M. Seidl,Lumonadio Luyengi,Harry H. S. Fong,Lilian U. Thompson +5 more
TL;DR: In vivo response can be predicted with confidence based on in vitro results, as a curvilinear relationship was observed between in vitro production and in vivo excretion of lignans and a high correlation was seen for SDG.
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Antioxidant flavonoid glycosides from Daphniphyllum calycinum
E. J. C. Gamez,Lumonadio Luyengi,Sang Kook Lee,L.-F. Zhu,Bin Zhou,Harry H. S. Fong,John M. Pezzuto,A. D. Kinghorn +7 more
TL;DR: A novel flavonoid diglycoside and a previously known compound were isolated from an ethyl acetate extract of Daphniphyllum calycinum leaves that showed significant activity in a 1,1-diphenyl-2-picrylhydrazyl (DPPH) free-radical assay.
Journal Article
Discovery of natural product chemopreventive agents utilizing HL-60 cell differentiation as a model.
TL;DR: It is concluded that the HL-60 cell differentiation system is a valid and useful model for the discovery of natural product cancer chemopreventive or chemotherapeutic agents.