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Luo Qi Zhou
Researcher at Huazhong University of Science and Technology
Publications - 7
Citations - 464
Luo Qi Zhou is an academic researcher from Huazhong University of Science and Technology. The author has contributed to research in topics: Microglia & Autophagy. The author has an hindex of 6, co-authored 7 publications receiving 185 citations.
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Journal ArticleDOI
Dual Functions of Microglia in Ischemic Stroke
Chuan Qin,Luo Qi Zhou,Xiao Tong Ma,Zi Wei Hu,Sheng Yang,Man Chen,Dale B. Bosco,Long Jun Wu,Dai Shi Tian +8 more
TL;DR: It is suggested that microglial activation is also critical for neurogenesis, angiogenesis, and synaptic remodeling, thereby promoting functional recovery after cerebral ischemia and the possible mechanisms controlling the post-ischemic activity of microglia.
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Microglial TLR4-dependent autophagy induces ischemic white matter damage via STAT1/6 pathway.
Chuan Qin,Qian Liu,Zi Wei Hu,Luo Qi Zhou,Ke Shang,Dale B. Bosco,Long Jun Wu,Dai Shi Tian,Wei Wang +8 more
TL;DR: TLR4-dependent autophagy regulates microglial polarization and induces ischemic white matter damage via STAT1/6 pathway, and TLR4 deficiency could mimic the phenomenon in microglia functional transformation, and exhibit a protective activity in chronic cerebral hypoperfusion.
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Microglia reprogram metabolic profiles for phenotype and function changes in central nervous system
Sheng Yang,Chuan Qin,Zi Wei Hu,Luo Qi Zhou,Hai Han Yu,Man Chen,Dale B. Bosco,Wei Wang,Long Jun Wu,Dai Shi Tian +9 more
TL;DR: In response to various types of environmental and cellular stress, microglia rapidly activate and exhibit either pro- or anti-inflammatory phenotypes to maintain tissue homeostasis as mentioned in this paper.
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Fingolimod promotes angiogenesis and attenuates ischemic brain damage via modulating microglial polarization
Ke Shang,Jia He,Jing Zou,Chuan Qin,Li Lin,Luo Qi Zhou,Lin Lin Yang,Long Jun Wu,Wei Wang,Ke Bin Zhan,Dai Shi Tian +10 more
TL;DR: Assessment of the pro-angiogenic potential of FTY720 in a murine model of acute cortical ischemic stroke indicated that FTY 720 treatment promoted angiogenesis via microglial M2 polarization and exerted neuroprotection in PT ischeic stroke.
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Proteomic profiling of plasma biomarkers in acute ischemic stroke due to large vessel occlusion
TL;DR: The identified 4-biomarker panel could provide diagnostic aid to the existing imaging modalities for AIS due to LVO, and the prognostic value of IGF2, LYVE1, and THBS1 was proved in predicting functional outcomes related to collateral status.