S
Sheng Yang
Researcher at Huazhong University of Science and Technology
Publications - 13
Citations - 4937
Sheng Yang is an academic researcher from Huazhong University of Science and Technology. The author has contributed to research in topics: Microglia & Medicine. The author has an hindex of 6, co-authored 6 publications receiving 2964 citations.
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Journal ArticleDOI
Dysregulation of Immune Response in Patients With Coronavirus 2019 (COVID-19) in Wuhan, China.
Chuan Qin,Luoqi Zhou,Ziwei Hu,Shuo-Qi Zhang,Sheng Yang,Yu Tao,Cuihong Xie,Ke Ma,Ke Shang,Wei Wang,Dai Shi Tian +10 more
TL;DR: Investigation of NLR and lymphocyte subsets is helpful in the early screening of critical illness, diagnosis and treatment of COVID-19 and shows the novel coronavirus might mainly act on lymphocytes, especially T lymphocytes.
Journal ArticleDOI
Dysregulation of Immune Response in Patients with COVID-19 in Wuhan, China
Chuan Qin,Luoqi Zhou,Ziwei Hu,Shuo-Qi Zhang,Sheng Yang,Yu Tao,Cuihong Xie,Ke Ma,Ke Shang,Wei Wang,Dai-Shi Tian +10 more
TL;DR: Patients with COVID-19 have lower level of regulatory T cells, and more obviously damaged in severe cases, compared with non-severe patients, which suggests surveillance of NLR and lymphocyte subsets is helpful in the early screening of critical illness, diagnosis and treatment of CO VID-19.
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Dual Functions of Microglia in Ischemic Stroke
Chuan Qin,Luo Qi Zhou,Xiao Tong Ma,Zi Wei Hu,Sheng Yang,Man Chen,Dale B. Bosco,Long Jun Wu,Dai Shi Tian +8 more
TL;DR: It is suggested that microglial activation is also critical for neurogenesis, angiogenesis, and synaptic remodeling, thereby promoting functional recovery after cerebral ischemia and the possible mechanisms controlling the post-ischemic activity of microglia.
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Clinical Characteristics and Outcomes of COVID-19 Patients With a History of Stroke in Wuhan, China.
Chuan Qin,Luoqi Zhou,Ziwei Hu,Sheng Yang,Shuo-Qi Zhang,Man Chen,Hai-Han Yu,Dai Shi Tian,Wei Wang +8 more
TL;DR: Stroke survivors who underwent COVID-19 developed more acute respiratory distress syndrome and received more noninvasive mechanical ventilation and were more likely to be held in the unit or die, compared with non-stroke history CO VID-19 patients.
Journal ArticleDOI
Signaling pathways involved in ischemic stroke: molecular mechanisms and therapeutic interventions
Chuan Qin,Sheng Yang,Yunjie Chu,Hang-xiang Zhang,Xiaoyi Pang,Lian Chen,Luoqi Zhou,Man Chen,Dai-Shi Tian,Wei Wang +9 more
TL;DR: In this paper , the authors describe the signaling pathways involved in ischemic stroke and categorize them based on the pathophysiological processes they participate in, and summarize the therapeutic approaches targeted various pathophysiology.