L
Lysiane Marcacci
Researcher at University of Geneva
Publications - 4
Citations - 2319
Lysiane Marcacci is an academic researcher from University of Geneva. The author has contributed to research in topics: Circadian rhythm & PER2. The author has an hindex of 4, co-authored 4 publications receiving 2159 citations.
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Journal ArticleDOI
Resetting of circadian time in peripheral tissues by glucocorticoid signaling.
Aurélio Balsalobre,Steven A. Brown,Lysiane Marcacci,François Tronche,Christoph Kellendonk,Holger M. Reichardt,Günther Schütz,Ueli Schibler +7 more
TL;DR: It is shown that the glucocorticoid hormone analog dexamethasone induces circadian gene expression in cultured rat-1 fibroblasts and transiently changes the phase of circadian gene Expression in liver, kidney, and heart, however, dexamETHasone does not affect cyclic geneexpression in neurons of the suprachiasmatic nucleus.
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Multiple signaling pathways elicit circadian gene expression in cultured Rat-1 fibroblasts
TL;DR: It is shown that cAMP, protein kinase C, glucocorticoid hormones and Ca2+ can all trigger a transient surge of Per1 transcription and elicit rhythmic gene expression in Rat-1 cells, suggesting that the SCN pacemaker may exploit multiple chemical cues to synchronize peripheral oscillators in vivo.
Journal ArticleDOI
The Transcription Factor DBP Affects Circadian Sleep Consolidation and Rhythmic EEG Activity
TL;DR: It is concluded that the transcriptional regulatory protein DBP modulates circadian and homeostatic aspects of sleep regulation and does modulate important clock outputs.
Journal ArticleDOI
DNA-binding specificity of PAR and C/EBP leucine zipper proteins: a single amino acid substitution in the C/EBP DNA-binding domain confers PAR-like specificity to C/EBP.
TL;DR: A single amino acid substitution mutant of C/EBP beta that increases its target site specificity is characterized, and as expected, DBP, is considerably less tolerant to deviations from the consensus site.