M
M A Marchionni
Researcher at Oregon Health & Science University
Publications - 2
Citations - 911
M A Marchionni is an academic researcher from Oregon Health & Science University. The author has contributed to research in topics: Complementary DNA & Gene mapping. The author has an hindex of 2, co-authored 2 publications receiving 895 citations.
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Cloning of the cDNA and gene for a human D2 dopamine receptor.
David K. Grandy,M A Marchionni,H. Makam,R E Stofko,M Alfano,L Frothingham,J B Fischer,K J Burke-Howie,James R. Bunzow,A C Server +9 more
TL;DR: In this paper, a human D2 dopamine receptor was sequenced from a pituitary cDNA library and sequenced with the deduced protein sequence is 96% identical with that of the cloned rat receptor with one major difference: the human receptor contains an additional 29 amino acids in its putative third cytoplasmic loop.
Journal Article
The human dopamine D2 receptor gene is located on chromosome 11 at q22-q23 and identifies a TaqI RFLP.
David K. Grandy,Michael Litt,L. Allen,James R. Bunzow,M A Marchionni,H. Makam,L. Reed,R. E. Magenis,Olivier Civelli +8 more
TL;DR: A search for RFLPs associated with D2DR identified a frequent two-allele TaqI RFLP that binds to the q22-q23 junction of chromosome 11 and is associated with antipsychotic drugs.