M
M. Beau Wanzer
Researcher at Northwestern University
Publications - 2
Citations - 397
M. Beau Wanzer is an academic researcher from Northwestern University. The author has contributed to research in topics: Inflammation & Small intestine. The author has an hindex of 2, co-authored 2 publications receiving 317 citations.
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Journal ArticleDOI
Uptake and Distribution of Ultrasmall Anatase TiO2 Alizarin Red S Nanoconjugates in Arabidopsis thaliana
Jasmina Kurepa,Tatjana Paunesku,Stefan Vogt,Hans Arora,Bryan M. Rabatic,Jinju Lu,M. Beau Wanzer,Gayle E. Woloschak,Jan A. Smalle +8 more
TL;DR: This is the first study describing uptake and distribution of the ultrasmall anatase TiO(2) in the plant model system Arabidopsis by modifying the nanoparticle surface with Alizarin red S and sucrose and demonstrating that nanoconjugates traversed cell walls, entered into plant cells, and accumulated in specific subcellular locations.
Journal ArticleDOI
Single administration of p2TA (AB103), a CD28 antagonist peptide, prevents inflammatory and thrombotic reactions and protects against gastrointestinal injury in total-body irradiated mice.
Salida Mirzoeva,Tatjana Paunesku,M. Beau Wanzer,Anat Shirvan,Raymond Kaempfer,Gayle E. Woloschak,William Small +6 more
TL;DR: The p2TA peptide delivery 24 h after irradiation led to improved morphology of villi and crypts, increased Cyclin D1 expression, decreased COX-2 staining and decreased numbers of macrophages in small intestine of irradiated mice, suggesting that attenuation of CD28 signaling is a promising therapeutic approach for mitigation of radiation-induced tissue injury.