PURPOSE: There is a lack of homogeneity in the terminology used in the context of patient safety related to medication. The aim of this review was to identify the terms and definitions used in patient safety related to medication within the scientific literature. METHODS: Original and review articles that were indexed between 1998 and 2008 in MEDLINE and EMBASE and contained terms used in patient safety related to medication were included. Terms and definitions were extracted and categorised according to whether its definition referred to the process of medication use, or to the clinical outcome of medication use, or both. RESULTS: Of 2564 articles, 147 were included. Sixty terms used in patient safety related to medication with 189 different definitions were identified. Among terms that referred only to the process of medication use (n = 23), medication error provided the greatest number of definitions (n = 29). Among terms that referred only to the clinical outcome of medication use (n = 31), adverse drug event provided the greatest number of definitions (n = 15). Finally, among terms that referred both to the process of use and to the clinical outcome of medication use (n = 13), drug-related problem provided the greatest number of definitions (n = 7). CONCLUSIONS: A multitude of terms and definitions are used in patient safety related to medication. This heterogeneity makes it difficult to compare the results among studies and to appreciate the true magnitude of the problem. Classifying and unifying the terminology is necessary to advance in patient safety strategies. Copyright © 2012 John Wiley & Sons, Ltd. Language: en

Terms used in patient safety related to medication: a literature review.

Predictors of prescription errors involving anticancer chemotherapy agents

All failures in some of the pharmacotherapy processes could be a potential risk to make mistakes that could to provoke damages in the patient. Thus, all service applying a cytostatic therapy to its patients must to establish a validation procedure of processes, beginning by prescription. In present paper an analysis of behavior of this process in the prescriptions was made including the carboplatin, cytostatic agent whose adverse effects are in general frequent, moderately significant and whose doses must to be adjusted taking into account the estimated clearance and the area under curve. The aim of present paper was to conduct a retrospective and descriptive study to identify the deficiencies during the pharmaceutical validation of this drug, included in the schemes of chemotherapy treatment in patients presenting with lung cancer. A total of 45 medical prescriptions were selected from patients aged over 51 with a similar behavior in both sexes where the non-small cells lung cancer was predominant, prevailing the error without type B damage (64) followed by error without type C damage (21). The potential type A errors were present in 26 opportunities; in eight of them the area under the curve was not signaled and in 18 there was not a dose change during the different cycles. We conclude that the pharmaceutical validation process is essential to avoid that the errors in prescription to reach patient.

Detección de errores potenciales de prescripción de carboplatino mediante validación farmacéutica

https://revistafarmaciahospitalaria.sefh.es/gdcr/index.php/fh/article/download/330/330

Validación de una clasificación de errores de medicación para su utilización en quimioterapia

http://www.aulamedica.es/fh/pdf/ING/330.pdf

Validating a Classification Scheme for Medication Errors to be Used in Chemotherapy

https://revistafarmaciahospitalaria.sefh.es/gdcr/index.php/fh/article/download/795/795

Validación farmacéutica y detección de errores de prescripción de antineoplásicos en pacientes oncohematológicos

Pharmaceutical Validation and Error Detection in the Prescription of Antineoplastics in Oncohaematological Patients

https://revistafarmaciahospitalaria.sefh.es/gdcr/index.php/fh/article/download/422/422

M.C. Garzás-Martín de Almagro

Papers

Validación farmacéutica y detección de errores de prescripción de antineoplásicos en pacientes oncohematológicos

Pharmaceutical Validation and Error Detection in the Prescription of Antineoplastics in Oncohaematological Patients

Efectividad y seguridad de 5-azacitidina en tres pacientes con sindrome mielodisplasico

Effectiveness and safety of 5-azacitidine in three patients with myelodysplastic syndromes