/pdf/aryl-aryl-bond-formation-one-century-after-the-discovery-of-1jdyxlkwix.pdf

Aryl-aryl bond formation one century after the discovery of the Ullmann reaction.

Metal Complexes as Photo- and Radiosensitizers

Pyrrolic and polypyrrolic anion binding agents

/pdf/rational-design-of-sequestering-agents-for-plutonium-and-4tqw2sjhps.pdf

Rational Design of Sequestering Agents for Plutonium and Other Actinides

Metal-Free Methods in the Synthesis of Macrocyclic Schiff Bases

Actinide expanded porphyrin complexes

The synthesis and characterization of the following heterosapphyrins is presented:  3,7,18,22-tetraethyl-2,8,12,13,17,23-hexamethyl-27-oxasapphyrin (5), 3,8,12,13,17,22-hexaethyl-2,7,18,23-tetramethyl-15,29-dioxasapphyrin (6), and 3,7,18,22-tetraethyl-2,8,12,13,17,23-hexamethyl-15,27,29-trioxasapphyrin (7). These macrocycles were synthesized from the hitherto unknown precursors methyl 3,4-dimethylfuran-2-carboxylate (11) and methyl 4-ethyl-3-methylfuran-2-carboxylate (12). Single-crystal X-ray diffraction structures of the bis(hydrochloric acid) salt (5a) and the bis(trifluoroacetic acid) salt (5b) of 5 and of the bis(hydrochloric acid) salt (6a) of 6 were obtained. These structures are compared to those of the parent all-aza sapphyrin 4. In this context, we report the first solid-state structural analysis of a trifluoroacetic acid salt of sapphyrin (4b). Crystals of 5a are triclinic, space group P1 in a cell of the dimensions a = 11.9686(13) A, b = 12.790(2) A, c = 16.236(2) A, α = 80.924(10)°, β = 88.8...

Synthesis and Characterization of All-Alkyl-Substituted Mono-, Di-, and Trioxosapphyrins

An efficient, high-yield preparation of substituted 2,2'-bipyrroles

This paper presents the synthesis of several new Schiff-base type expanded porphyrins. A dimeric, tetraazacyclodotetradecane-linked texaphyrin system has been prepared. It, as its gadoliniu'n(II1) adduct, displays a relaxivity in aqueous solution that is roughly 5 times higher than the benchmark texaphyrin monomer currently undergoing human clinical trials as a potential MRI enhancing and X-ray radiation sensitizing drug. Polymeric gadolinium(1II) texaphyrin species, ,derived from poly-L-lysine and a glycosylated poly-L-lysine, have also been prepared, they too display greatly enhanced relaxivities. In work along different lines, the synthesis of an "expanded" texaphyrin has been effected and the construction of two "three dimensional" texaphyrin-inspired targets accomplished. These latter define a new class of pyrrolic cryptands.

/pdf/new-texaphyrin-type-expanded-porphyrins-428kk26otx.pdf

M. C. Hoehner

Papers

Actinide expanded porphyrin complexes

Synthesis and Characterization of All-Alkyl-Substituted Mono-, Di-, and Trioxosapphyrins

An efficient, high-yield preparation of substituted 2,2'-bipyrroles

New texaphyrin-type expanded porphyrins

Erratum to “Actinide expanded porphyrin complexes”