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M

M. den Heijer

Researcher at Radboud University Nijmegen Medical Centre

Publications -  74
Citations -  14527

M. den Heijer is an academic researcher from Radboud University Nijmegen Medical Centre. The author has contributed to research in topics: Homocysteine & Population. The author has an hindex of 33, co-authored 74 publications receiving 13983 citations. Previous affiliations of M. den Heijer include Radboud University Nijmegen & VU University Medical Center.

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Journal ArticleDOI

The MTHFR 677C->T polymorphism and the risk of congenital heart defects: a literature review and meta-analysis.

TL;DR: This relatively small meta-analysis found no substantial evidence of increased CHD risk in individuals with MTHFR 677CT and TT genotypes and further larger studies and well-defined phenotypic subcategory analyses are needed to decide whether the MTHfr 677C-->T polymorphism of the affected child and/or their mother is truly a risk factor for the development of CHDs.
Journal Article

Thyroid function in patients with proteinuria.

TL;DR: Patients with proteinuria have higher TSH levels, consistent with urinary loss of thyroid hormones, however, these urinary losses do not result in overt, clinically relevant, hypothyroidism, and the role of subclinical hypothy thyroid function parameters in these patients needs further evaluation.
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Apolipoprotein B, non-HDL cholesterol and LDL cholesterol for identifying individuals at increased cardiovascular risk.

TL;DR: A Apolipoprotein B, non‐HDL cholesterol and LDL cholesterol for identifying individuals at increased cardiovascular risk and the need for further studies are outlined.
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Multilayer compression bandaging in the acute phase of deep-vein thrombosis has no effect on the development of the post-thrombotic syndrome

TL;DR: Immediate multilayer compression bandaging in the acute phase of DVT is effective in reducing edema and complaints in the first week, but has no effect on thrombus regression, valve incompetence and the development of clinical PTS after 1 year.
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Detecting psychiatric disorders in medical practice using the General Health Questionnaire. Why do cut-off scores vary ?

TL;DR: The data demonstrate that the use of disembedded or separate versions of the questionnaire, together with variation in the case criteria can be a major explanation for variation in cut-off scores that was observed in previous studies.