M
M.F. Favata
Researcher at University of Virginia
Publications - 1
Citations - 27
M.F. Favata is an academic researcher from University of Virginia. The author has contributed to research in topics: Reductase & Coenzyme A. The author has an hindex of 1, co-authored 1 publications receiving 27 citations.
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Post-transcriptional Regulation of 3-Hydroxy-3-methylglutaryl Coenzyme-A Reductase by 3β-Hydroxy-Lanost-8-en-32-Al, an Intermediate in the Conversion of Lanosterol to Cholesterol
TL;DR: Data are presented which suggest that 3 beta-hydroxy-lanost-8-en-32-al inhibits HMGR gene expression by reducing the translational efficiency of the HMGR mRNA, and structurally similar posttranscriptional regulators of HMGR suppress enzyme activity, at least in part, by different mechanisms.