M
M. Navarro
Publications - 4
Citations - 3387
M. Navarro is an academic researcher. The author has contributed to research in topics: Oxaliplatin & Irinotecan. The author has an hindex of 3, co-authored 4 publications receiving 3289 citations.
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Journal ArticleDOI
Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial
Jean-Yves Douillard,David Cunningham,Arnaud Roth,M. Navarro,Roger D James,P. Karasek,P. Jandik,Timothy Iveson,Joseph C. Carmichael,M. Alakl,G. Gruia,Lucile Awad,Philippe Rougier +12 more
TL;DR: Irinotecan combined with fluorouracil and calcium folinate was well-tolerated and increased response rate, time to progression, and survival, with a later deterioration in quality of life.
Journal ArticleDOI
Capecitabine plus oxaliplatin (XELOX) versus 5-fluorouracil/folinic acid plus oxaliplatin (FOLFOX-4) as second-line therapy in metastatic colorectal cancer: a randomized phase III noninferiority study
Mace L. Rothenberg,John Cox,Charles Butts,M. Navarro,Yung-Jue Bang,Rakesh Goel,Simon Gollins,L.L. Siu,S. Laguerre,David Cunningham +9 more
TL;DR: XELOX is noninferior to FOLFOX-4 when administered as second-line treatment in patients with metastatic colorectal cancer after prior irinotecan-based chemotherapy.
Journal ArticleDOI
Phase III trial of capecitabine + oxaliplatin (XELOX) vs. 5-fluorouracil (5-FU), leucovorin (LV), and oxaliplatin (FOLFOX4) as 2nd-line treatment for patients with metastatic colorectal cancer (MCRC)
Mace L. Rothenberg,M. Navarro,Charles Butts,Yung-Jue Bang,John Cox,Rakesh Goel,Simon Gollins,Lillian L. Siu,David Cunningham +8 more
TL;DR: A phase III study comparing XELOX with FOLFOX4 in patients who had received prior treatment with irinotecan in combination with bolus and/or infusional 5-FU/LV for MCRC, which met the primary objective of the study.
Journal ArticleDOI
3012 ORAL Capecitabine + oxaliplatin (XELOX) vs. 5-FU/LV + oxaliplatin (FOLFOX4) as second-line treatment for patients with metastatic colorectal cancer (MCRC): Phase III trial results
Mace L. Rothenberg,M. Navarro,Charles Butts,Yung-Jue Bang,John Cox,Rakesh Goel,S. Gollins,L. Siu,David Cunningham +8 more