M P Carrieri

TL;DR: Prescription of buprenorphine DMT may increase adherence to HAART among HIV-infected opiate-dependent patients and reducing the negative impact of stressful life-events through psychosocial interventions should be considered, even for those who have stopped using drugs.

TL;DR: Initiation of treatment at a stage of preserved immunity is associated with a more durable virological response under protease inhibitor, and every effort should be made to monitor and strengthen adherence to therapy, even in patients having early virology response.

TL;DR: To improve long-term patient outcomes for those at risk of adherence failure, tailor-made patient-specific psychosocial interventions and regimen-based strategies with improved tolerance need to be implemented.

TL;DR: Logistic regression showed that lack of a stable relationship, active drug injection, and depression were independently associated with adherence failure and patients’ counseling for facilitating maintenance of adherence to HAART over time should focus on prevention of drug use, provision of social support and consider the potential impact of difficulties with treatment on psychological well-being.

TL;DR: The results obtained on a large sample of HIV-infected patients with extensive follow-up underline the need for a regular monitoring of patients–immunological status and for a better management of their experience with hepatitis C and HAART.