M. Steven Oberste

TL;DR: The VP1 sequences derived from the RT-snPCR products allow rapid phylogenetic and molecular epidemiologic analysis of strains circulating during the EV season and comparison with EV sequences from past seasons or from different locations around the world.

TL;DR: Hospital admissions for severe respiratory illness have continued at both facilities at rates higher than expected for this time of year and investigations into suspected clusters in other jurisdictions are ongoing.

TL;DR: On August 19, 2014, CDC was notified by Children's Mercy Hospital in Kansas City, Missouri, of an increase (relative to the same period in previous years) in patients examined and hospitalized with severe respiratory illness, including some admitted to the pediatric intensive care unit An increase also was noted in detections of rhinovirus/enterovirus by a multiplex polymerase chain reaction assay in nasopharyngeal specimens obtained during August 5-19.

TL;DR: EV71 infection should be considered in young children presenting with aseptic meningitis, encephalitis, acute flaccid paralysis, or acute cardiopulmonary collapse, and likely remains unrecognized in other parts of the United States, because EV-PCR of cerebrospinal fluid frequently yields negative results.

TL;DR: Empirical data suggest this AFM cluster was likely associated with the large outbreak of EV-D68-associated respiratory illness, although direct laboratory evidence linking AFM with EV- D68 remains inconclusive.