S
Senthilkumar K. Sakthivel
Researcher at Centers for Disease Control and Prevention
Publications - 24
Citations - 1222
Senthilkumar K. Sakthivel is an academic researcher from Centers for Disease Control and Prevention. The author has contributed to research in topics: Coronavirus & Middle East respiratory syndrome. The author has an hindex of 12, co-authored 22 publications receiving 858 citations. Previous affiliations of Senthilkumar K. Sakthivel include Battelle Memorial Institute & National Center for Immunization and Respiratory Diseases.
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Journal ArticleDOI
US CDC Real-Time Reverse Transcription PCR Panel for Detection of Severe Acute Respiratory Syndrome Coronavirus 2.
Xiaoyan Lu,Lijuan Wang,Senthilkumar K. Sakthivel,Brett Whitaker,Janna Murray,Shifaq Kamili,Brian Lynch,Lakshmi Malapati,Stephen A. Burke,Jennifer L Harcourt,Azaibi Tamin,Natalie J. Thornburg,Julie Villanueva,Stephen Lindstrom +13 more
TL;DR: A diagnostic panel consisting of 3 real-time reverse transcription PCR assays targeting the nucleocapsid gene and evaluated use of these assays for detecting SARS-CoV-2 infection, which obtained no false-positive amplifications with other human coronaviruses or common respiratory pathogens.
Journal ArticleDOI
Acute Flaccid Myelitis in the United States, August-December 2014: Results of Nationwide Surveillance.
James J. Sejvar,Adriana S. Lopez,Margaret M. Cortese,Eyal Leshem,Daniel M. Pastula,Lisa Miller,Carol A. Glaser,Anita Kambhampati,Anita Kambhampati,Kayoko Shioda,Kayoko Shioda,Negar Aliabadi,Marc Fischer,Nicole Gregoricus,Robert S. Lanciotti,W. Allan Nix,Senthilkumar K. Sakthivel,D. Scott Schmid,Jane F. Seward,Suxiang Tong,M. Steven Oberste,Mark A. Pallansch,Daniel R. Feikin +22 more
TL;DR: Empirical data suggest this AFM cluster was likely associated with the large outbreak of EV-D68-associated respiratory illness, although direct laboratory evidence linking AFM with EV- D68 remains inconclusive.
Posted ContentDOI
First 12 patients with coronavirus disease 2019 (COVID-19) in the United States
Stephanie A Kujawski,Karen K. Wong,Jennifer P Collins,Lauren Epstein,Marie E Killerby,Claire M Midgley,Glen R. Abedi,N Seema Ahmed,Olivia Almendares,Francisco N Alvarez,Kayla N. Anderson,Sharon Balter,Vaughn Barry,Karri Bartlett,Karlyn D. Beer,Michael Ben-Aderet,Isaac Benowitz,Holly M. Biggs,Alison M. Binder,Stephanie R. Black,Brandon Bonin,Catherine M. Brown,Hollianne Bruce,Jonathan Bryant-Genevier,Alicia P. Budd,Diane Buell,Rachel Bystritsky,Jordan Cates,E. Matt Charles,Kevin Chatham-Stephens,Nora Chea,Howard Chiou,Demian Christiansen,Victoria T Chu,Sara Cody,Max Cohen,Erin E. Conners,Aaron T. Curns,Vishal Dasari,Patrick Dawson,Traci DeSalvo,George A. Diaz,Matthew Donahue,Suzanne Donovan,Lindsey M. Duca,Keith Erickson,Mathew D. Esona,Suzanne Evans,Jeremy A. Falk,Leora R. Feldstein,Martin Fenstersheib,Marc Fischer,Rebecca Fisher,Chelsea Foo,Marielle J Fricchione,Oren Friedman,Alicia M. Fry,Romeo R. Galang,Melissa M. Garcia,Susa I. Gerber,Graham Gerrard,Isaac Ghinai,Prabhu Gounder,Jonathan Grein,Cheri Grigg,Jeffrey D. Gunzenhauser,Gary I. Gutkin,Meredith Haddix,Aron J. Hall,George S Han,Jennifer L Harcourt,Kathleen Harriman,Thomas Haupt,Amber K. Haynes,Michelle Holshue,Cora Hoover,Jennifer C. Hunter,Max W. Jacobs,Claire Jarashow,Michael A. Jhung,Kiran Joshi,Talar Kamali,Shifaq Kamili,Lindsay Kim,Moon Kim,Jan King,Hannah L Kirking,Amanda Kita-Yarbro,Rachel Klos,Miwako Kobayashi,Anna Kocharian,Kenneth Komatsu,Ram Koppaka,Jennifer E Layden,Yan Li,Scott Lindquist,Stephen Lindstrom,Ruth Link-Gelles,Joana Y Lively,Michelle Livingston,Kelly Lo,Jennifer Lo,Xiaoyan Lu,Brian Lynch,Lawrence C. Madoff,Lakshmi Malapati,Gregory Marks,Mariel Marlow,Glenn E. Mathisen,Nancy McClung,Olivia L McGovern,Tristan D. McPherson,Mitali Mehta,Audrey Meier,Lynn Mello,Sung-Sil Moon,Margie Morgan,Ruth N. Moro,Janna Murray,Rekha Murthy,Shannon A. Novosad,Sara E. Oliver,Jennifer O'Shea,Massimo Pacilli,Clinton R. Paden,Mark A. Pallansch,Manisha Patel,Sajan Patel,Isabel Pedraza,Satish K. Pillai,Talia Pindyck,Ian W. Pray,Krista Queen,Nichole Quick,Heather Reese,Brian Rha,Heather J. Rhodes,Susan Robinson,Philip Robinson,Melissa A Rolfes,Janell Routh,Rachel Rubin,Sarah L. Rudman,Senthilkumar K. Sakthivel,Sarah Scott,Christopher Shepherd,Varun Shetty,Ethan A. Smith,Shanon Smith,Bryan Stierman,William V. Stoecker,Rebecca Sunenshine,Regina Sy-Santos,Azaibi Tamin,Ying Tao,Dawn Terashita,Natalie J. Thornburg,Suxiang Tong,Elizabeth Traub,Ahmet Tural,Anna Uehara,Timothy M. Uyeki,Grace M Vahey,Jennifer R. Verani,Elsa Villarino,Megan J. Wallace,Lijuan Wang,John T. Watson,Matthew Westercamp,Brett Whitaker,Sarah Wilkerson,Rebecca C. Woodruff,Jonathan M. Wortham,Tiffany Wu,Amy Xie,Anna R Yousaf,Matthew Zahn,Jing Zhang +177 more
TL;DR: In 12 patients with mild to moderately severe illness, SARS-CoV-2 RNA and viable virus were detected early, and prolonged RNA detection suggests the window for diagnosis is long.
Journal ArticleDOI
Middle East Respiratory Syndrome Coronavirus Infection Dynamics and Antibody Responses among Clinically Diverse Patients, Saudi Arabia.
Hail M. Al-Abdely,Claire M Midgley,Abdulrahim M Alkhamis,Glen R. Abedi,Xiaoyan Lu,Alison M. Binder,Khalid H. Alanazi,Azaibi Tamin,Weam M. Banjar,Sandra Lester,Osman Abdalla,Rebecca M. Dahl,Mutaz Mohammed,Suvang Trivedi,Homoud S. Algarni,Senthilkumar K. Sakthivel,Abdullah Algwizani,Fahad Bafaqeeh,Abdullah G. Alzahrani,Ali A. Alsharef,Raafat F. Alhakeem,Hani Jokhdar,Sameeh S. Ghazal,Natalie J. Thornburg,Natalie J. Thornburg,Natalie J. Thornburg,Dean D. Erdman,Abdullah M. Assiri,John T. Watson,Susan I. Gerber +29 more
TL;DR: It was found that diabetes mellitus among survivors was associated with prolonged MERS-CoV RNA detection in the respiratory tract, and development of robust neutralizing serum antibody responses during the second and third week of illness was not sufficient for patient recovery or virus clearance.
Journal ArticleDOI
Comparison of fast-track diagnostics respiratory pathogens multiplex real-time RT-PCR assay with in-house singleplex assays for comprehensive detection of human respiratory viruses
Senthilkumar K. Sakthivel,Brett Whitaker,Xiaoyan Lu,Danielle Bruna Leal Oliveira,Danielle Bruna Leal Oliveira,Lauren J. Stockman,Shifaq Kamili,M. Steven Oberste,Dean D. Erdman +8 more
TL;DR: Most FTDRP assays performed comparably with in-house assays for most viruses while offering enhanced throughput and easy integration by laboratories using conventional real-time PCR instrumentation.