M
Madeleine Dupont
Researcher at Centre national de la recherche scientifique
Publications - 7
Citations - 1821
Madeleine Dupont is an academic researcher from Centre national de la recherche scientifique. The author has contributed to research in topics: Familial Mediterranean fever & MEFV. The author has an hindex of 4, co-authored 6 publications receiving 1725 citations.
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Journal ArticleDOI
A candidate gene for familial Mediterranean fever
Alain Bernot,Christian Clepet,Corinne Dasilva,Catherine Devaud,Jean-Louis Petit,Christophe Caloustian,Corinne Cruaud,Delphine Samson,Françoise Pulcini,Jean Weissenbach,Roland Heilig,Cécile Notanicola,Cécile Domingo,Michael Rozenbaum,Eldad Ben-Chetrit,Rezzan Topaloglu,Marie Dewalle,Christiane Dross,Philippe Hadjari,Madeleine Dupont,Jacques Demaille,Isabelle Touitou,Nizar Smaoui,Brigitte Nedelec,Jean-Philippe Mery,Habiba Chaabouni,Marc Delpech,Gilles Grateau +27 more
TL;DR: A minimal co-segregating region of 60 kb containing the FMF gene (MEFV) is defined and one of these transcripts encodes a new protein (marenostrin) related to the ret-finger protein and to butyrophilin.
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Non-Founder Mutations in the MEFV Gene Establish This Gene as the Cause of Familial Mediterranean Fever (FMF)
Alain Bernot,Corinne Da Silva,Jean-Louis Petit,Corinne Cruaud,Christophe Caloustian,Valérie Castet,Mehdi Ahmed-Arab,Christiane Dross,Madeleine Dupont,Daniel Cattan,Nizar Smaoui,Catherine Dodé,Christophe Pêcheux,Brigitte Nedelec,Jean Medaxian,Michel Rozenbaum,Itshak Rosner,Marc Delpech,Gilles Grateau,Jacques Demaille,Jean Weissenbach,Isabelle Touitou +21 more
TL;DR: The marenostrin/pyrin-encoding gene is definitively established as the MEFV locus, and mutations found in 120 apparently non-founder FMF chromosomes are confirmed.
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Phenotype-genotype correlation in Jewish patients suffering from familial Mediterranean fever (FMF).
Marie Dewalle,Cécile Domingo,Michel Rozenbaum,Eldad Ben-Chetrit,Daniel Cattan,Alain Bernot,Christiane Dross,Madeleine Dupont,Cécile Notarnicola,Micha Levy,Itzhak Rosner,Jacques Demaille,Isabelle Touitou +12 more
TL;DR: It was shown that homozygosity for this mutation was significantly associated with a more severe form of the disease and the present result strongly suggests the potential prognostic value of the presence of this mutation.
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Simple variant t(8;21) acute myeloid leukemias harbor insertions of the AML1 or ETO genes
Sylvie Taviaux,Véronique Brunel,Madeleine Dupont,Francisca Fernandez,Concepcion Ferraz,Nadine Carbuccia,Danielle Sainty,Jacques Demaille,Françoise Birg,Marina Lafage-Pochitaloff +9 more
TL;DR: Two acute myeloid leukemias with simple variant t(8;21) probably occurred through complex mechanisms, combining translocation and insertion of chromosomal segments, leading to functional AML1‐ETO fusion signals.
Journal ArticleDOI
Mapping the Three‐Dimensional Nanostructure of the Ionic Liquid–Solid Interface Using Atomic Force Microscopy and Molecular Dynamics Simulations
Aaron Elbourne,Madeleine Dupont,Rashad Kariuki,Nastaran Meftahi,Torben Daeneke,Tamar L. Greaves,Christopher F McConville,G Bryant,Saffron J. Bryant,Quinn A Besford,Andrew J. Christofferson +10 more
TL;DR: In this paper , the 3D nanostructure of the EAN-mica interface is investigated using a combination of 1D, 2D, and 3D amplitude modulated-atomic force microscopy and molecular dynamics simulations.