M
Magdalena Kozakowska
Researcher at Jagiellonian University
Publications - 39
Citations - 1614
Magdalena Kozakowska is an academic researcher from Jagiellonian University. The author has contributed to research in topics: Heme oxygenase & Angiogenesis. The author has an hindex of 18, co-authored 35 publications receiving 1373 citations.
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Journal ArticleDOI
The role of oxidative stress in skeletal muscle injury and regeneration: focus on antioxidant enzymes
TL;DR: Current knowledge regarding the role of oxidative stress and systems of enzymatic antioxidant defence in muscular regeneration after both acute injury and persistent muscular degeneration are presented.
Journal ArticleDOI
Interplay Between Heme Oxygenase-1 and miR-378 Affects Non-Small Cell Lung Carcinoma Growth, Vascularization, and Metastasis
Klaudia Skrzypek,Magdalena Tertil,Slawomir Golda,Maciej Ciesla,Kazimierz Weglarczyk,Guillaume Collet,Alan Guichard,Magdalena Kozakowska,Jorge Boczkowski,Halina Was,Tomasz Gil,Jarosław Kużdżał,Lucie Muchová,Libor Vítek,Agnieszka Loboda,Alicja Jozkowicz,Claudine Kieda,Jozef Dulak +17 more
TL;DR: In vitro and in vivo data indicate that the interplay between HMOX1 and miR-378 significantly modulates NSCLC progression and angiogenesis, suggesting miR -378 as a new therapeutic target.
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Heme oxygenase-1 accelerates cutaneous wound healing in mice.
Anna Grochot-Przeczek,Radosław Lach,Jacek Mis,Klaudia Skrzypek,Malgorzata Gozdecka,Patrycja Sroczynska,Milena Dubiel,Andrzej J. Rutkowski,Magdalena Kozakowska,Anna Zagorska,Jacek Walczynski,Halina Was,Jerzy Kotlinowski,Justyna Drukala,Krzysztof Kurowski,Claudine Kieda,Yann Herault,Jozef Dulak,Alicja Jozkowicz +18 more
TL;DR: Induction of HO-1 in wounded skin was relatively weak and delayed in diabetic mice, in which also angiogenesis and wound closure were impaired, and may be associated with delayedHO-1 upregulation and can be improved by HO- 1 gene transfer.
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Heme Oxygenase-1 Inhibits Myoblast Differentiation by Targeting Myomirs
Magdalena Kozakowska,Maciej Ciesla,Anna Stefanska,Klaudia Skrzypek,Halina Was,Agnieszka Jazwa,Anna Grochot-Przeczek,Jerzy Kotlinowski,Agnieszka Szymula,Aleksandra Bartelik,Milena Mazan,Oleksandr Yagensky,Urszula Florczyk,Krzysztof Lemke,Anna Zebzda,Grzegorz Dyduch,Witold Nowak,Krzysztof Szade,Jacek Stępniewski,Marcin Majka,Rafal Derlacz,Agnieszka Loboda,Jozef Dulak,Alicja Jozkowicz +23 more
TL;DR: HMOX1 improves the survival of myoblasts, but concurrently through regulation of myomirs, may act similarly to oncogenes, increasing the risk of hyperplastic growth of myogenic precursors.
Journal ArticleDOI
MicroRNAs as biomarkers of disease onset
Maciej Ciesla,Klaudia Skrzypek,Magdalena Kozakowska,Agnieszka Loboda,Alicja Jozkowicz,Jozef Dulak +5 more
TL;DR: Small, noncoding RNA molecules with the ability to posttranscriptionally regulate gene expression via targeting the 3′ untranslated region of messenger RNAs are critical for normal cellular functions such as the regulation of the cell cycle, differentiation, and apoptosis.