M
Magdalena Niemira
Researcher at Medical University of Białystok
Publications - 48
Citations - 666
Magdalena Niemira is an academic researcher from Medical University of Białystok. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 11, co-authored 32 publications receiving 350 citations. Previous affiliations of Magdalena Niemira include Gdańsk University of Technology.
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Journal ArticleDOI
Molecular Signature of Subtypes of Non-Small-Cell Lung Cancer by Large-Scale Transcriptional Profiling: Identification of Key Modules and Genes by Weighted Gene Co-Expression Network Analysis (WGCNA)
Magdalena Niemira,Francois Collin,Anna Szalkowska,Agnieszka Bielska,Karolina Chwiałkowska,Joanna Reszeć,Jacek Niklinski,Miroslaw Kwasniewski,Adam Kretowski +8 more
TL;DR: CTLA4, MZB1, NIP7, and BUB1B in ADC, as well as GNG11 and CCNB2 in SCC, are novel top hub genes in modules associated with tumour size, SUVmax, and recurrence-free survival.
Journal ArticleDOI
The rs340874 PROX1 type 2 diabetes mellitus risk variant is associated with visceral fat accumulation and alterations in postprandial glucose and lipid metabolism.
Adam Kretowski,Edyta Adamska,Katarzyna Maliszewska,Natalia Wawrusiewicz-Kurylonek,Anna Citko,Joanna Goscik,Witold Bauer,Juliusz Wilk,Anna Golonko,Magdalena Waszczeniuk,Danuta Lipinska,Justyna Hryniewicka,Magdalena Niemira,Magdalena Paczkowska,Michal Ciborowski,Maria Gorska +15 more
TL;DR: In this paper, the functional/phenotypic differences related to rs340874 single-nucleotide polymorphism in the PROX1 gene were evaluated in 945 subjects of Polish origin, including 634 without previously known dysglycemia.
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Proteomics biomarkers for non-small cell lung cancer.
TL;DR: This review briefly describes the latest reports in proteomic studies of NSCLC and contains a summary of the methods used to detect proteomic markers in different types of biological material and their clinical application as diagnostic, prognostic, and predictive biomarkers compiled on the basis of the most recent literature and own experience.
Journal ArticleDOI
Prenatal circulating microRNA signatures of foetal Down syndrome
Monika Zbucka-Kretowska,Magdalena Niemira,Magdalena Paczkowska-Abdulsalam,Agnieszka Bielska,Anna Szalkowska,Ewa Parfieniuk,Michal Ciborowski,Slawomir Wolczynski,Adam Kretowski +8 more
TL;DR: Information is yielded on DS-specific miRNA expression signature, which can further help to design a panel of miRNAs as a non-invasive test for DS diagnosis and it is believed that identified miRNAAs may attend in the pathogenesis of DS and would potentially make a significant role for the future preventive therapies.
Journal ArticleDOI
The imidazoacridinone antitumor drug, C-1311, is metabolized by flavin monooxygenases but not by cytochrome P450s.
Agnieszka Potęga,Emilia Dabrowska,Magdalena Niemira,Agata Kot-Wasik,Sebastien Ronseaux,Colin J. Henderson,C. Roland Wolf,Zofia Mazerska +7 more
TL;DR: It is shown that, whereas liver P450 isoenzymes were involved in the metabolism of C-1311 to a limited extent, FMO plays a significant role in the microsomal transformations of this compound, which is also a specific substrate of UGT1A1.