S
Slawomir Wolczynski
Researcher at Medical University of Białystok
Publications - 245
Citations - 4512
Slawomir Wolczynski is an academic researcher from Medical University of Białystok. The author has contributed to research in topics: Estrogen receptor & Estrogen. The author has an hindex of 31, co-authored 237 publications receiving 4029 citations. Previous affiliations of Slawomir Wolczynski include Polish Academy of Sciences.
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Journal ArticleDOI
Kallmann syndrome: mutations in the genes encoding prokineticin-2 and prokineticin receptor-2.
Catherine Dodé,Luis Augusto Teixeira,Jacqueline Levilliers,Corinne Fouveaut,Philippe Bouchard,Marie Laure Kottler,James Lespinasse,Anne Lienhardt-Roussie,Michèle Mathieu,Alexandre Moerman,Graeme Morgan,Arnaud Murat,Jean Edmont Toublanc,Slawomir Wolczynski,Marc Delpech,Christine Petit,Jacques Young,J.-P. Hardelin +17 more
TL;DR: Findings reveal that insufficient prokineticin-signaling through PROKR2 leads to abnormal development of the olfactory system and reproductive axis in man and shed new light on the complex genetic transmission of Kallmann syndrome.
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Oxidative stress markers in preovulatory follicular fluid in humans.
TL;DR: The intensity of peroxidation in the Graafian follicle is much lower than that in serum, suggestive of the presence of efficient antioxidant defence systems in the direct milieu of the oocyte before ovulation.
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A Comparative Phenotypic Study of Kallmann Syndrome Patients Carrying Monoallelic and Biallelic Mutations in the Prokineticin 2 or Prokineticin Receptor 2 Genes
Julie Sarfati,Anne Guiochon-Mantel,Philippe Rondard,Isabelle Arnulf,Alfons Garcia-Piñero,Slawomir Wolczynski,Sylvie Brailly-Tabard,Maud Bidet,Maria Ramos-Arroyo,Michèle Mathieu,Anne Lienhardt-Roussie,Graeme Morgan,Zinet Turki,Catherine Bremont,James Lespinasse,Hélène Du Boullay,Nathalie Chabbert-Buffet,Sébastien Jacquemont,Gérard Reach,Nicole De Talence,Paolo Tonella,Bernard Conrad,F. Despert,Bruno Delobel,Thierry Brue,Claire Bouvattier,Sylvie Cabrol,Michel Pugeat,Arnaud Murat,Philippe Bouchard,Jean-Pierre Hardelin,Catherine Dodé,Jacques Young +32 more
TL;DR: Male patients carrying biallelic mutations in PROK2 or PROKR2 have a less variable and on average a more severe reproductive phenotype than patients carrying monoallelic mutationsIn these genes.
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Advances in the Molecular Pathophysiology, Genetics, and Treatment of Primary Ovarian Insufficiency
Ilpo Huhtaniemi,Outi Hovatta,Antonio La Marca,Gabriel Livera,Danielle Monniaux,Luca Persani,Abdelkader Heddar,Katarzyna Jarzabek,Triin Laisk-Podar,Andres Salumets,Juha S. Tapanainen,Juha S. Tapanainen,Reiner A. Veitia,Jenny A. Visser,Peter Wieacker,Slawomir Wolczynski,Micheline Misrahi +16 more
TL;DR: NGS will provide a genetic diagnosis leading to genetic/therapeutic counseling: first, defects in meiosis or DNA repair genes may predispose to tumors; and second, specific gene defects may predict the risk of rapid loss of a persistent ovarian reserve, an important determinant in fertility preservation.
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Serum visfatin in relation to insulin resistance and markers of hyperandrogenism in lean and obese women with polycystic ovary syndrome
Irina Kowalska,Marek Straczkowski,Agnieszka Nikolajuk,Agnieszka Adamska,Monika Karczewska-Kupczewska,Elzbieta Otziomek,Slawomir Wolczynski,Maria Gorska +7 more
TL;DR: Visfatin is associated with insulin resistance and markers of hyperandrogenism in lean PCOS patients and in lean women, visfatin was associated with serum testosterone and free androgen index.