M
Mahmood Ghassemi
Researcher at University of Illinois at Chicago
Publications - 30
Citations - 1208
Mahmood Ghassemi is an academic researcher from University of Illinois at Chicago. The author has contributed to research in topics: Wound healing & Medicine. The author has an hindex of 12, co-authored 25 publications receiving 1100 citations. Previous affiliations of Mahmood Ghassemi include Rush University.
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Journal ArticleDOI
Role of Virion-associated Glycosylphosphatidylinositol-linked Proteins CD55 and CD59 in Complement Resistance of Cell Line-derived and Primary Isolates of HIV-1
Mohammed Saifuddin,Charles J. Parker,Mark E. Peeples,Miroslaw K. Gorny,Susan Zolla-Pazner,Mahmood Ghassemi,Isabelle A. Rooney,John P. Atkinson,Gregory T. Spear +8 more
TL;DR: Results show that CD55 and CD59 are incorporated into HIV-1 particles and function to protect virions from complement-mediated destruction, and they are the first report of host cell proteins functioning in protection of HIV- 1 from immune effector mechanisms.
Journal ArticleDOI
Nucleotide Biosynthesis Is Critical for Growth of Bacteria in Human Blood
Shalaka Samant,Hyunwoo Lee,Mahmood Ghassemi,Juan Chen,James L. Cook,Alexander S. Mankin,Alexander A. Neyfakh +6 more
TL;DR: It is indicated that de novo nucleotide biosynthesis represents the single most critical metabolic function for bacterial growth in blood and the corresponding enzymes as putative antibiotic targets for the treatment of bloodstream infections are revealed.
Journal Article
Host cell-derived complement control proteins CD55 and CD59 are incorporated into the virions of two unrelated enveloped viruses. Human T cell leukemia/lymphoma virus type I (HTLV-I) and human cytomegalovirus (HCMV).
Gregory T. Spear,Nell S. Lurain,Charles J. Parker,Mahmood Ghassemi,Gregory H. Payne,Mohammed Saifuddin +5 more
TL;DR: These experiments show that HTLV-I and HCMV acquire C control proteins from host cells, a mechanism by which a variety of enveloped viruses may acquire resistance to C-mediated destruction.
Journal ArticleDOI
Activation of Human Immunodeficiency Virus Type 1 Expression by Gardnerella vaginalis
TL;DR: G. vaginalis lysates were found to significantly stimulate HIV expression in monocytoid cells and activated HIV long-terminal repeat transcription in HIV-infected cells and increased NF-kappaB binding activity, indicating an effect by G. vaginais on HIV transcription.
Journal ArticleDOI
Induction of Human Immunodeficiency Virus Type 1 Expression by Anaerobes Associated with Bacterial Vaginosis
TL;DR: This study supports the idea that treatment of BV might serve as a preventive measure to reduce the risk of HIV transmission, and suggests a mechanism by which disturbances in vaginal flora could lead to a higher rate of sexual transmission of HIV.