Makoto Otsuka

TL;DR: Findings suggest that the zinc-containing tricalcium phosphate is a biomaterial that has a pharmaceutical effect of promoting bone formation.

TL;DR: The results of this study showed that the CAPs possessed an MES distribution and therefore provided further support that M ES distribution is a common phenomenon, regardless of the method of CAP synthesis, and supported a view that microstrain, rather than crystallite size, is the dominant factor governing the effective solubility of the CAP's and dental enamel.

TL;DR: Methods for the preparation of polymorphs of indomethacin (IMC) were studied and it was concluded that the transformation followed kinetics corresponding to two-dimensional growth of nuclei (Avrami equation), and the activation energy was calculated to be 14.2 kcal/mol from the Arrhenius plot.

TL;DR: This hydroxyapatite cement drug-delivery system can be applied in the treatment of osteomyelitis and infected compound fractures and correlated well with the Higuchi model.

TL;DR: Calcium phosphate is a suitable carrier of zinc, an essential element that has stimulatory effects on bone formation in vitro and in vivo as well as an inhibitory effect on osteoclastic bone resorption in vitro.