M
Malcolm B. Hodgins
Researcher at University of Glasgow
Publications - 31
Citations - 1577
Malcolm B. Hodgins is an academic researcher from University of Glasgow. The author has contributed to research in topics: Connexin & Hair follicle. The author has an hindex of 18, co-authored 31 publications receiving 1519 citations.
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Journal ArticleDOI
Localization of androgen receptors in human skin by immunohistochemistry: implications for the hormonal regulation of hair growth, sebaceous glands and sweat glands.
TL;DR: This study indicates that androgens regulate sebaceous gland and hair growth by acting upon two different types of target cells, the epithelial sebocytes of seboidal glands and the mesenchymal cells of the hair follicle dermal papilla.
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trans-dominant inhibition of connexin-43 by mutant connexin-26: implications for dominant connexin disorders affecting epidermal differentiation
Fatima Rouan,Thomas W. White,Nkecha Brown,Aileen Taylor,Thomas W. Lucke,David L. Paul,Colin S. Munro,Jouni Uitto,Malcolm B. Hodgins,Gabriela Richard +9 more
TL;DR: A trans-dominant negative effect of Cx26 mutants in vitro is demonstrated, for the first time, and support a novel concept suggesting that the principal mechanism for manifestation of dominant GJB2 mutations in the skin is their dominant interference with the function of wtCx43.
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Genetics of Psoriasis: Paternal Inheritance and a Locus on Chromosome 6p
A. David Burden,Malcolm B. Hodgins,David Tillman,Shaban Javed,Michael Connor,Mark E.S. Bailey +5 more
TL;DR: In this paper, the authors carried out linkage analysis in a large number of families with well-characterized psoriasis and found strong evidence for linkage to chromosome 6p (maximum two point LOD score 4.63 at D6S291).
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Upregulation of connexin 26 is a feature of keratinocyte differentiation in hyperproliferative epidermis, vaginal epithelium, and buccal epithelium.
Tom Lucke,Rukhsana Choudhry,Russell Thom,Inger-Sofie Selmer,A. David Burden,Malcolm B. Hodgins +5 more
TL;DR: Observations would be consistent with a role for connexin 26 containing gap junctions during both early and later stages of keratinocyte differentiation in hyperplastic epidermis and in vaginal and buccal epithelia.
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An immunohistochemical study of androgen, oestrogen and progesterone receptors in the vulva and vagina
TL;DR: Objective Tomap potential sites of sex steroid action in the human vulva are identified and these sites should be investigated in further studies to determine their importance in women's sexual development.