M
Malène Sutren
Researcher at Institut national de la recherche agronomique
Publications - 15
Citations - 3438
Malène Sutren is an academic researcher from Institut national de la recherche agronomique. The author has contributed to research in topics: Population & Lactobacillus casei. The author has an hindex of 14, co-authored 15 publications receiving 3307 citations.
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Journal ArticleDOI
Direct Analysis of Genes Encoding 16S rRNA from Complex Communities Reveals Many Novel Molecular Species within the Human Gut
Antonia Suau,Antonia Suau,Régis Bonnet,Malène Sutren,Jean Jacques Godon,Glenn R. Gibson,Matthew D. Collins,Joël Doré +7 more
TL;DR: The majority of generated rDNA sequences did not correspond to known organisms and clearly derived from hitherto unknown species within this human gut microflora, including Clostridium coccoides and Eubacterium rectale.
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Alterations of the dominant faecal bacterial groups in patients with Crohn's disease of the colon
Philippe Seksik,Lionel Rigottier-Gois,Geneviève Gramet,Malène Sutren,P Pochart,P Marteau,R. Jian,Joël Doré +7 more
TL;DR: Enterobacteria were observed significantly more frequently in CD than in health, and more than 30% of the dominant flora belonged to yet undefined phylogenetic groups, suggesting the biodiversity of the microflora remains high in patients with CD.
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Biodiversity of the mucosa‐associated microbiota is stable along the distal digestive tract in healthy individuals and patients with IBD
Patricia Lepage,Philippe Seksik,Malène Sutren,Marie-France de la Cochetière,Raymond Jian,Philippe Marteau,Joël Doré +6 more
TL;DR: Results confirm that the dominant species differ between the mucosa‐associated and fecal microbiota and show that, in a given individual, the microbiota is relatively stable along the distal digestive tract, showing a slight evolution in dominant species diversity from the ileum to the rectum, in both healthy subjects and patients with IBD.
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Fusobacterium prausnitzii and related species represent a dominant group within the human fecal flora.
Antonia Suau,Violaine Rochet,Abdelghani Sghir,Geneviève Gramet,Stéphanie Brewaeys,Malène Sutren,Lionel Rigottier-Gois,Joël Doré +7 more
TL;DR: This work designed and validated a specific rRNA-targeted oligonucleotide probe, called S-*-Fprau-0645-a-A-23, to accurately detect and quantify F. prausnitzii and relatives within the human fecal microflora.
Journal ArticleDOI
Design and validation of 16S rRNA probes to enumerate members of the Clostridium leptum subgroup in human faecal microbiota.
Christophe Lay,Malène Sutren,Violaine Rochet,Katiana Saunier,Joël Doré,Lionel Rigottier-Gois +5 more
TL;DR: To improve detection and description of members of the C. leptum subgroup, the Clep 866 group probe was developed and allowed for the first time the detection of all members found in this phylogenetic group in human faecal microbiota.