M
Malgorzata Setkowicz
Researcher at Jagiellonian University
Publications - 9
Citations - 681
Malgorzata Setkowicz is an academic researcher from Jagiellonian University. The author has contributed to research in topics: Aspirin & Angioedema. The author has an hindex of 7, co-authored 9 publications receiving 654 citations.
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Journal ArticleDOI
EAACI/GA2LEN guideline: aspirin provocation tests for diagnosis of aspirin hypersensitivity
Ewa Nizankowska-Mogilnicka,Grazyna Bochenek,Lucyna Mastalerz,Monika Swierczyńska,César Picado,G Scadding,Marek L. Kowalski,Malgorzata Setkowicz,J. Ring,Knut Brockow,Claus Bachert,Stefan Wöhrl,Barbro Dahlén,Andrzej Szczeklik +13 more
TL;DR: Aspirin and other nonsteroidal anti‐inflammatory drugs (NSAIDs) are among the most common causes of adverse drug reactions, and majority of them are of the hypersensitivity type.
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Safety of cyclooxygenase 2 inhibitors and increased leukotriene synthesis in chronic idiopathic urticaria with sensitivity to nonsteroidal anti-inflammatory drugs.
Artur Zembowicz,Lucyna Mastalerz,Malgorzata Setkowicz,Waldemar Radziszewski,Andrzej Szczeklik +4 more
TL;DR: Sensitivity to NSAIDs in CIU is associated with overproduction of cysteinyl leukotrienes and mast cell activation and most likely depends on inhibition of cyclooxygenase 1.
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Clinical course and urinary eicosanoids in patients with aspirin-induced urticaria followed up for 4 years.
TL;DR: Aspirin hypersensitivity manifesting as urticaria/angioedema remains present after 4 years in about two thirds of patients, and aspirin-precipitated skin reactions associate with increased excretion of LTE(4) and PGD(2).
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The alpha-chain of high-affinity receptor for IgE (FcepsilonRIalpha) gene polymorphisms and serum IgE levels.
Daniel P. Potaczek,Marek Sanak,Lucyna Mastalerz,Malgorzata Setkowicz,M. Kaczor,E. Nizankowska,Andrzej Szczeklik +6 more
TL;DR: The α subunit of the high‐affinity receptor for immunoglobulin‐E (IgE) (FcɛRI) plays a major role in the pathogenesis of allergy, but there are only two published studies on itsα subunit genetic variability in allergic diseases.
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Familial aggregation of aspirin‐induced urticaria and leukotriene C4 synthase allelic variant
TL;DR: In patients with chronic idiopathic urticaria who reacted adversely to aspirin, the frequency of the −444C allele of the leukotriene C4 synthase gene (LTC4S) was higher than in patients who tolerated aspirin well.