M
Malgorzata Wanczyk
Researcher at Medical University of Warsaw
Publications - 4
Citations - 284
Malgorzata Wanczyk is an academic researcher from Medical University of Warsaw. The author has contributed to research in topics: CD20 & Chronic lymphocytic leukemia. The author has an hindex of 3, co-authored 4 publications receiving 251 citations.
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Aminolevulinic Acid (ALA) as a Prodrug in Photodynamic Therapy of Cancer
Malgorzata Wachowska,Angelika Muchowicz,Malgorzata Firczuk,Magdalena Gabrysiak,Magdalena Winiarska,Malgorzata Wanczyk,Kamil Bojarczuk,Jakub Golab +7 more
TL;DR: Since PpIX is a potent photosensitizer this metabolic pathway can be exploited in photodynamic therapy (PDT), this is an already approved therapeutic strategy making ALA one of the most successful prodrugs used in cancer treatment.
Journal ArticleDOI
HDACi--going through the mechanisms
Malgorzata Wanczyk,Katarzyna Roszczenko,Katarzyna Marcinkiewicz,Kamil Bojarczuk,Michal Kowara,Magdalena Winiarska +5 more
TL;DR: Recent advances in the understanding of biology of HDACs and mechanism of action of their inhibitors are summarized.
Journal ArticleDOI
Prenyltransferases Regulate CD20 Protein Levels and Influence Anti-CD20 Monoclonal Antibody-mediated Activation of Complement-dependent Cytotoxicity
Magdalena Winiarska,Dominika Nowis,Jacek Bil,Eliza Glodkowska-Mrowka,Angelika Muchowicz,Malgorzata Wanczyk,Kamil Bojarczuk,Michal Dwojak,Malgorzata Firczuk,Ewa Wilczek,Malgorzata Wachowska,Katarzyna Roszczenko,Marta Miaczynska,Justyna Chlebowska,Grzegorz W. Basak,Jakub Golab,Jakub Golab +16 more
TL;DR: These studies indicate that CD20 expression can be modulated by FTIs, and the combination of FTIs with anti-CD20 mAbs is a promising therapeutic approach, and its efficacy should be examined in patients with B-cell tumors.
Prenyltransferases Regulate CD20 Protein Levels and Influence Anti-CD20 Monoclonal Antibody-mediated
Magdalena Winiarska,Dominika Nowis,Jacek Bil,Eliza Glodkowska-Mrowka,Angelika Muchowicz,Malgorzata Wanczyk,Kamil Bojarczuk,Michal Dwojak,Malgorzata Firczuk,Ewa Wilczek,Malgorzata Wachowska,Katarzyna Roszczenko,Marta Miaczynska,Justyna Chlebowska,Wladyslaw Basak,Jakub Golab,Fromthe ‡ DepartmentofImmunology +16 more
TL;DR: In this article, the influence of farnesyltransferase inhibitors (FTIs) on CD20 expression and antitumor activity of anti-CD20 mAbs was investigated.